Anlotinib combined with penpulimab in the treatment of advanced adult thoracic spinal osteosarcoma: a case report

BackgroundSpinal osteosarcoma is a rare and prognostically poor subtype of osteosarcoma, with limited efficacy from traditional chemoradiotherapy. The potential of targeted therapy combined with immunotherapy requires further exploration.Case SummaryA 53-year-old female with stage IV thoracic spinal...

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Bibliographic Details
Main Authors: Xiaochun Chen, Xianqin Li, Haiying Zhao, Jinwen Qu, Xiaojuan Li, Chuan Lin, Zhiping Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1599496/full
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