Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy
Oncocytic tumors, composed of eosinophilic, mitochondria-rich cells, can occur in several locations throughout the body. These tumors can occur in the adrenal cortex and are rarely malignant. We report a case of a patient presenting with an incidental adrenal mass which was later diagnosed as a onco...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2015/515071 |
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| author | Andrew C. Harbin Andrew Chen Siddharth Bhattacharyya Jasvir S. Khurana Joshua R. Kaplan Daniel D. Eun |
| author_facet | Andrew C. Harbin Andrew Chen Siddharth Bhattacharyya Jasvir S. Khurana Joshua R. Kaplan Daniel D. Eun |
| author_sort | Andrew C. Harbin |
| collection | DOAJ |
| description | Oncocytic tumors, composed of eosinophilic, mitochondria-rich cells, can occur in several locations throughout the body. These tumors can occur in the adrenal cortex and are rarely malignant. We report a case of a patient presenting with an incidental adrenal mass which was later diagnosed as a oncocytic adrenocortical neoplasm (OAN). The patient is a 53-year-old man found to have a 7.2 cm right adrenal mass, incidentally found by computed tomography (CT). After metabolic workup was negative, a right robotic adrenalectomy (RA) was performed. Pathologic analysis revealed clusters of large cells with abundant eosinophilic and granular cytoplasm, consistent with OAN. This pathology is rare, with only about 150 cases described in the literature. It occurs in females 2.5 times more frequently and more commonly on the left side. Diagnosis is usually made by imaging criteria, typically with CT or magnetic resonance imaging (MRI). Treatment is generally surgical, since OAN can be malignant in some cases. Differentiation between benign and malignant OAN is done based on the Lin-Weiss-Bisceglia criteria and can be difficult. If malignancy is diagnosed, recurrence is common and close surveillance should be performed. |
| format | Article |
| id | doaj-art-b888089ac8b748caa4be2befc01e96ae |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
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| series | Case Reports in Urology |
| spelling | doaj-art-b888089ac8b748caa4be2befc01e96ae2025-02-03T05:47:48ZengWileyCase Reports in Urology2090-696X2090-69782015-01-01201510.1155/2015/515071515071Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted AdrenalectomyAndrew C. Harbin0Andrew Chen1Siddharth Bhattacharyya2Jasvir S. Khurana3Joshua R. Kaplan4Daniel D. Eun5Department of Urology, Temple University Hospital, 3401 N Broad Street, Philadelphia, PA 19140, USADepartment of Urology, Temple University Hospital, 3401 N Broad Street, Philadelphia, PA 19140, USADepartment of Pathology, Temple University Hospital, 3401 N Broad Street, Philadelphia, PA 19140, USADepartment of Pathology, Temple University Hospital, 3401 N Broad Street, Philadelphia, PA 19140, USADepartment of Urology, Temple University Hospital, 3401 N Broad Street, Philadelphia, PA 19140, USADepartment of Urology, Temple University Hospital, 3401 N Broad Street, Philadelphia, PA 19140, USAOncocytic tumors, composed of eosinophilic, mitochondria-rich cells, can occur in several locations throughout the body. These tumors can occur in the adrenal cortex and are rarely malignant. We report a case of a patient presenting with an incidental adrenal mass which was later diagnosed as a oncocytic adrenocortical neoplasm (OAN). The patient is a 53-year-old man found to have a 7.2 cm right adrenal mass, incidentally found by computed tomography (CT). After metabolic workup was negative, a right robotic adrenalectomy (RA) was performed. Pathologic analysis revealed clusters of large cells with abundant eosinophilic and granular cytoplasm, consistent with OAN. This pathology is rare, with only about 150 cases described in the literature. It occurs in females 2.5 times more frequently and more commonly on the left side. Diagnosis is usually made by imaging criteria, typically with CT or magnetic resonance imaging (MRI). Treatment is generally surgical, since OAN can be malignant in some cases. Differentiation between benign and malignant OAN is done based on the Lin-Weiss-Bisceglia criteria and can be difficult. If malignancy is diagnosed, recurrence is common and close surveillance should be performed.http://dx.doi.org/10.1155/2015/515071 |
| spellingShingle | Andrew C. Harbin Andrew Chen Siddharth Bhattacharyya Jasvir S. Khurana Joshua R. Kaplan Daniel D. Eun Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy Case Reports in Urology |
| title | Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy |
| title_full | Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy |
| title_fullStr | Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy |
| title_full_unstemmed | Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy |
| title_short | Oncocytic Adrenocortical Neoplasm Diagnosed after Robot-Assisted Adrenalectomy |
| title_sort | oncocytic adrenocortical neoplasm diagnosed after robot assisted adrenalectomy |
| url | http://dx.doi.org/10.1155/2015/515071 |
| work_keys_str_mv | AT andrewcharbin oncocyticadrenocorticalneoplasmdiagnosedafterrobotassistedadrenalectomy AT andrewchen oncocyticadrenocorticalneoplasmdiagnosedafterrobotassistedadrenalectomy AT siddharthbhattacharyya oncocyticadrenocorticalneoplasmdiagnosedafterrobotassistedadrenalectomy AT jasvirskhurana oncocyticadrenocorticalneoplasmdiagnosedafterrobotassistedadrenalectomy AT joshuarkaplan oncocyticadrenocorticalneoplasmdiagnosedafterrobotassistedadrenalectomy AT danieldeun oncocyticadrenocorticalneoplasmdiagnosedafterrobotassistedadrenalectomy |