Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal Cells

This study was conducted to determine the effect of bone marrow stromal cells (BMSCs) on progesterone level during pregnancy in ewes. Flurogestone Acetate Sponges 40 mg, followed by 400 i.u. Equine chorionic gonadotropin (eCG) were used to synchronize estrus and ovulation. The animals were divided...

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Main Authors: A.A.Omar, T.R. Mohammed, Salah M.A.AL-Kubaisi
Format: Article
Language:English
Published: College of Veterinary Medicine, University of Fallujah 2019-12-01
Series:مجلة الانبار للعلوم البيطرية
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Online Access:https://www.anbarjvs.edu.iq/wp-content/uploads/2020/04/13.pdf
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author A.A.Omar
T.R. Mohammed
Salah M.A.AL-Kubaisi
author_facet A.A.Omar
T.R. Mohammed
Salah M.A.AL-Kubaisi
author_sort A.A.Omar
collection DOAJ
description This study was conducted to determine the effect of bone marrow stromal cells (BMSCs) on progesterone level during pregnancy in ewes. Flurogestone Acetate Sponges 40 mg, followed by 400 i.u. Equine chorionic gonadotropin (eCG) were used to synchronize estrus and ovulation. The animals were divided into three equal groups (5 animals for each group). The 1st and 2nd group injected intravenously after eCG injection with 1x108 and 2x108 respectively with BMSCs while the 3rd group was injected with normal saline which serve as a control group. Blood samples were collected during pregnancy, at day 10, 21, 85 from the jugular vein. At day 10, 21 the results showed that there was a significant difference (p≤0.05) in the level of progesterone between treated groups as compared with the control group. While there was no significant difference between different groups at day 85. It was concluded from this study that BMSCs have a beneficial effect in ewe’s reproductive system, by increasing the level of progesterone at early pregnancy.
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publishDate 2019-12-01
publisher College of Veterinary Medicine, University of Fallujah
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series مجلة الانبار للعلوم البيطرية
spelling doaj-art-b883ea0132554a1993399b2aee94b2912025-08-20T03:39:22ZengCollege of Veterinary Medicine, University of Fallujahمجلة الانبار للعلوم البيطرية1999-65272707-06032019-12-0112210.37940/AJVS.2019.12.2.13Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal CellsA.A.Omar T.R. Mohammed Salah M.A.AL-KubaisiThis study was conducted to determine the effect of bone marrow stromal cells (BMSCs) on progesterone level during pregnancy in ewes. Flurogestone Acetate Sponges 40 mg, followed by 400 i.u. Equine chorionic gonadotropin (eCG) were used to synchronize estrus and ovulation. The animals were divided into three equal groups (5 animals for each group). The 1st and 2nd group injected intravenously after eCG injection with 1x108 and 2x108 respectively with BMSCs while the 3rd group was injected with normal saline which serve as a control group. Blood samples were collected during pregnancy, at day 10, 21, 85 from the jugular vein. At day 10, 21 the results showed that there was a significant difference (p≤0.05) in the level of progesterone between treated groups as compared with the control group. While there was no significant difference between different groups at day 85. It was concluded from this study that BMSCs have a beneficial effect in ewe’s reproductive system, by increasing the level of progesterone at early pregnancy.https://www.anbarjvs.edu.iq/wp-content/uploads/2020/04/13.pdfbone marrow stromal cellsprogesteronepregnancyewes.
spellingShingle A.A.Omar
T.R. Mohammed
Salah M.A.AL-Kubaisi
Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal Cells
مجلة الانبار للعلوم البيطرية
bone marrow stromal cells
progesterone
pregnancy
ewes.
title Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal Cells
title_full Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal Cells
title_fullStr Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal Cells
title_full_unstemmed Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal Cells
title_short Progesterone Levels During Pregnancy in Ewes Treated with Bone Marrow Stromal Cells
title_sort progesterone levels during pregnancy in ewes treated with bone marrow stromal cells
topic bone marrow stromal cells
progesterone
pregnancy
ewes.
url https://www.anbarjvs.edu.iq/wp-content/uploads/2020/04/13.pdf
work_keys_str_mv AT aaomar progesteronelevelsduringpregnancyinewestreatedwithbonemarrowstromalcells
AT trmohammed progesteronelevelsduringpregnancyinewestreatedwithbonemarrowstromalcells
AT salahmaalkubaisi progesteronelevelsduringpregnancyinewestreatedwithbonemarrowstromalcells