Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica
Edible salty-flavored Chinese materia medica (ESCM) refers to a category of traditional Chinese medicine (TCM) that also serve as food, characterized by their salty flavor. According to the TCM theory, ESCM can soften and disperse knots, thus potentially offering benefits for cancer prevention and t...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-06-01
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| Series: | Frontiers in Pharmacology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1598978/full |
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| author | Zhongqi Shen Meng Yu Zhenguo Wang |
| author_facet | Zhongqi Shen Meng Yu Zhenguo Wang |
| author_sort | Zhongqi Shen |
| collection | DOAJ |
| description | Edible salty-flavored Chinese materia medica (ESCM) refers to a category of traditional Chinese medicine (TCM) that also serve as food, characterized by their salty flavor. According to the TCM theory, ESCM can soften and disperse knots, thus potentially offering benefits for cancer prevention and treatment. With cancer remaining a major global health challenge, its primary prevention strategies, especially through dietary modification, are crucial. ESCM have recently garnered substantial attention, due to their remarkable clinical efficacy and low side-effect profile. Researches on ESCM demonstrate that they mainly function through inhibition of cancer cell proliferation, migration, and invasion, induction of cancer cell apoptosis and autophagy, regulation of the cell cycle, suppression of tumor angiogenesis, and anti-inflammatory and anti-oxidant properties. Herein, we systematically explore the well-documented ESCM’s extracts or constituents with explicit anti-cancer properties, alongside their underlying mechanisms and pathways. The review further highlights both the primary preventions and clinical trials of ESCM-related products, offering valuable insights for the development of novel dietary approaches and therapeutic interventions in cancer management. |
| format | Article |
| id | doaj-art-b8776d7839fc4da7b00fed0daae631f5 |
| institution | OA Journals |
| issn | 1663-9812 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj-art-b8776d7839fc4da7b00fed0daae631f52025-08-20T02:09:31ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-06-011610.3389/fphar.2025.15989781598978Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medicaZhongqi Shen0Meng Yu1Zhenguo Wang2Institute of Chinese Medical Literature and Culture, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaInnovative Institute of Chinese Medicine and Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaInstitute of Chinese Medical Literature and Culture, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaEdible salty-flavored Chinese materia medica (ESCM) refers to a category of traditional Chinese medicine (TCM) that also serve as food, characterized by their salty flavor. According to the TCM theory, ESCM can soften and disperse knots, thus potentially offering benefits for cancer prevention and treatment. With cancer remaining a major global health challenge, its primary prevention strategies, especially through dietary modification, are crucial. ESCM have recently garnered substantial attention, due to their remarkable clinical efficacy and low side-effect profile. Researches on ESCM demonstrate that they mainly function through inhibition of cancer cell proliferation, migration, and invasion, induction of cancer cell apoptosis and autophagy, regulation of the cell cycle, suppression of tumor angiogenesis, and anti-inflammatory and anti-oxidant properties. Herein, we systematically explore the well-documented ESCM’s extracts or constituents with explicit anti-cancer properties, alongside their underlying mechanisms and pathways. The review further highlights both the primary preventions and clinical trials of ESCM-related products, offering valuable insights for the development of novel dietary approaches and therapeutic interventions in cancer management.https://www.frontiersin.org/articles/10.3389/fphar.2025.1598978/fulledible salty-flavored Chinese materia medicatraditional Chinese medicineanti-cancerprimary preventionhealth products |
| spellingShingle | Zhongqi Shen Meng Yu Zhenguo Wang Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica Frontiers in Pharmacology edible salty-flavored Chinese materia medica traditional Chinese medicine anti-cancer primary prevention health products |
| title | Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica |
| title_full | Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica |
| title_fullStr | Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica |
| title_full_unstemmed | Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica |
| title_short | Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica |
| title_sort | research progress on the anti cancer mechanisms of edible salty flavored chinese materia medica |
| topic | edible salty-flavored Chinese materia medica traditional Chinese medicine anti-cancer primary prevention health products |
| url | https://www.frontiersin.org/articles/10.3389/fphar.2025.1598978/full |
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