Evidence suggesting that microglia make amyloid from neuronally expressed APP: a hypothesis
Abstract While APP is largely neuonally expressed, Aβ amyloid is largely produced by microglia as the clearance mechanisms for damaged membranes becomes overwhelmed.
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| Main Authors: | John Hardy, Patrick Lewis |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Molecular Neurodegeneration |
| Online Access: | https://doi.org/10.1186/s13024-025-00847-8 |
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