Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025

Chikungunya virus re-emerged on Réunion Island in August 2024, 18 years after a first major outbreak. Analysis of 173 genomes from the current epidemic reveals a monophyletic clade with mutations linked to adaptation to Aedes albopictus mosquitoes, including E1-A226V. Bayesian inference suggests onl...

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Main Author: Marie-Christine Jaffar-Bandjee
Format: Article
Language:English
Published: European Centre for Disease Prevention and Control 2025-06-01
Series:Eurosurveillance
Subjects:
Online Access:https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.22.2500344
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author Marie-Christine Jaffar-Bandjee
author_facet Marie-Christine Jaffar-Bandjee
author_sort Marie-Christine Jaffar-Bandjee
collection DOAJ
description Chikungunya virus re-emerged on Réunion Island in August 2024, 18 years after a first major outbreak. Analysis of 173 genomes from the current epidemic reveals a monophyletic clade with mutations linked to adaptation to Aedes albopictus mosquitoes, including E1-A226V. Bayesian inference suggests only brief cryptic circulation before detection. The same lineage was also detected on Mayotte Island in March 2025. Continued spread and confirmed travel-related cases in mainland France and globally highlight the risk of wider regional and international dissemination.
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spelling doaj-art-b871e2be36a841e2b48fd3159d0b353f2025-08-20T02:32:48ZengEuropean Centre for Disease Prevention and ControlEurosurveillance1560-79172025-06-01302210.2807/1560-7917.ES.2025.30.22.2500344http://instance.metastore.ingenta.com/content/eurosurveillance/30/22Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025Marie-Christine Jaffar-Bandjee0Laboratoire de microbiologie, CHU de la Réunion-Site Nord, Saint-Denis, Réunion, FranceChikungunya virus re-emerged on Réunion Island in August 2024, 18 years after a first major outbreak. Analysis of 173 genomes from the current epidemic reveals a monophyletic clade with mutations linked to adaptation to Aedes albopictus mosquitoes, including E1-A226V. Bayesian inference suggests only brief cryptic circulation before detection. The same lineage was also detected on Mayotte Island in March 2025. Continued spread and confirmed travel-related cases in mainland France and globally highlight the risk of wider regional and international dissemination.https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.22.2500344Genomic analysismolecular epidemiologysurveillanceemergenceChikungunyaarbovirus
spellingShingle Marie-Christine Jaffar-Bandjee
Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025
Eurosurveillance
Genomic analysis
molecular epidemiology
surveillance
emergence
Chikungunya
arbovirus
title Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025
title_full Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025
title_fullStr Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025
title_full_unstemmed Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025
title_short Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025
title_sort genomic insights into the re emergence of chikungunya virus on reunion island france 2024 to 2025
topic Genomic analysis
molecular epidemiology
surveillance
emergence
Chikungunya
arbovirus
url https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.22.2500344
work_keys_str_mv AT mariechristinejaffarbandjee genomicinsightsintothereemergenceofchikungunyavirusonreunionislandfrance2024to2025