Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
Abstract Novelty and Impact Statement: Our findings suggest that soluble folate receptor (sFR) could be used in both the initial diagnosis and surveillance of patients with ovarian cancer. Our cohort constitutes one of the largest comparison groups for sFR analyzed so far. We have defined the backgr...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-03-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.1944 |
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| _version_ | 1832576225266106368 |
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| author | Batoul Farran Samet Albayrak Judith Abrams Michael A. Tainsky Nancy K. Levin Robert Morris Larry H. Matherly Manohar Ratnam Ira Winer |
| author_facet | Batoul Farran Samet Albayrak Judith Abrams Michael A. Tainsky Nancy K. Levin Robert Morris Larry H. Matherly Manohar Ratnam Ira Winer |
| author_sort | Batoul Farran |
| collection | DOAJ |
| description | Abstract Novelty and Impact Statement: Our findings suggest that soluble folate receptor (sFR) could be used in both the initial diagnosis and surveillance of patients with ovarian cancer. Our cohort constitutes one of the largest comparison groups for sFR analyzed so far. We have defined the background level of sFR using healthy volunteers. This is also the first study to prospectively follow patients in the surveillance setting to concurrently identify differential changes in tumor markers CA‐125 and sFR. |
| format | Article |
| id | doaj-art-b86d3a7480844c61bdfcceaf39caea1a |
| institution | Kabale University |
| issn | 2045-7634 |
| language | English |
| publishDate | 2019-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj-art-b86d3a7480844c61bdfcceaf39caea1a2025-01-31T08:47:42ZengWileyCancer Medicine2045-76342019-03-018392092710.1002/cam4.1944Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillanceBatoul Farran0Samet Albayrak1Judith Abrams2Michael A. Tainsky3Nancy K. Levin4Robert Morris5Larry H. Matherly6Manohar Ratnam7Ira Winer8Department of Oncology Wayne State University and Karmanos Cancer Institute Detroit MichiganDepartment of Obstetrics and Gynecology Wayne State University Detroit MichiganDepartment of Oncology Wayne State University and Karmanos Cancer Institute Detroit MichiganDepartment of Oncology Wayne State University and Karmanos Cancer Institute and Center for Molecular Medicine and Genetics Detroit MichiganDepartment of Oncology Wayne State University and Karmanos Cancer Institute Detroit MichiganDepartment of Oncology, Division of Gynecologic Oncology Wayne State University and Karmanos Cancer Institute Detroit MichiganDepartments of Oncology and Pharmacology Wayne State University and Karmanos Cancer Institute Detroit MichiganDepartment of Oncology Wayne State University and Karmanos Cancer Institute Detroit MichiganDepartment of Oncology, Division of Gynecologic Oncology Wayne State University and Karmanos Cancer Institute Detroit MichiganAbstract Novelty and Impact Statement: Our findings suggest that soluble folate receptor (sFR) could be used in both the initial diagnosis and surveillance of patients with ovarian cancer. Our cohort constitutes one of the largest comparison groups for sFR analyzed so far. We have defined the background level of sFR using healthy volunteers. This is also the first study to prospectively follow patients in the surveillance setting to concurrently identify differential changes in tumor markers CA‐125 and sFR.https://doi.org/10.1002/cam4.1944biomarkersgynecologic oncologytranslational research |
| spellingShingle | Batoul Farran Samet Albayrak Judith Abrams Michael A. Tainsky Nancy K. Levin Robert Morris Larry H. Matherly Manohar Ratnam Ira Winer Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance Cancer Medicine biomarkers gynecologic oncology translational research |
| title | Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance |
| title_full | Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance |
| title_fullStr | Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance |
| title_full_unstemmed | Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance |
| title_short | Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance |
| title_sort | serum folate receptor α sfr in ovarian cancer diagnosis and surveillance |
| topic | biomarkers gynecologic oncology translational research |
| url | https://doi.org/10.1002/cam4.1944 |
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