Exploring Conformational Transitions in Biased and Balanced Ligand Binding of GLP-1R

The glucagon-like peptide-1 receptor (GLP-1R), which belongs to the class B1 G protein-coupled receptor (GPCR) family, is an important target for treatment of metabolic disorders, including type 2 diabetes and obesity. The growing interest in GLP-1R-based therapies is driven by the development of va...

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Bibliographic Details
Main Authors: Marc Xu, Horst Vogel, Shuguang Yuan
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/15/3216
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