Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey

Abstract Background There are few effective treatments for eating disorders (EDs), and new interventions are urgently needed. The MEDication and other drugs For Eating Disorders (“MED–FED”) survey investigated the lived experience of adults with EDs regarding their prescription and non-prescription...

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Main Authors: Sarah-Catherine Rodan, Noah Meez, Sophie Lloyd-Hurwitz, Miguel A. Bedoya-Pérez, Anastasia Suraev, Natasha Sommer, Kayla Greenstien, Sarah Maguire, Iain S. McGregor
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Eating Disorders
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Online Access:https://doi.org/10.1186/s40337-025-01328-5
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author Sarah-Catherine Rodan
Noah Meez
Sophie Lloyd-Hurwitz
Miguel A. Bedoya-Pérez
Anastasia Suraev
Natasha Sommer
Kayla Greenstien
Sarah Maguire
Iain S. McGregor
author_facet Sarah-Catherine Rodan
Noah Meez
Sophie Lloyd-Hurwitz
Miguel A. Bedoya-Pérez
Anastasia Suraev
Natasha Sommer
Kayla Greenstien
Sarah Maguire
Iain S. McGregor
author_sort Sarah-Catherine Rodan
collection DOAJ
description Abstract Background There are few effective treatments for eating disorders (EDs), and new interventions are urgently needed. The MEDication and other drugs For Eating Disorders (“MED–FED”) survey investigated the lived experience of adults with EDs regarding their prescription and non-prescription drugs use. Psychedelic drugs were highly rated in this survey for their impact on ED symptoms and general mental health. Here, we provide a more granular analysis of a subset of the data pertaining to psychedelic drug use from this survey. Methods The MED–FED survey recruited adults who self-reported either a clinically diagnosed ED or disordered eating that was currently undiagnosed but causing significant distress. The demographics of recent and lifetime psychedelic users relative to non-users were examined, as well as their use of other prescription and non-prescription drugs, and co-morbid conditions. Qualitative analysis was used to examine themes emerging from open-ended comments around use of psychedelic drugs. Results Of the 5247 participants who completed the survey, 1699/5247 (32.4%) reported lifetime psychedelic use, with 1019/5247 (19.4%) having used in the last 12 months. Typical use involved infrequent consumption, once or twice per year, of psilocybin, LSD, 2-CB, or DMT. Those who reported recent psychedelic use were younger and less likely to currently use prescription drugs or to have been recently hospitalised for their ED. They were more likely to use other non-prescription drugs (e.g. cannabis, ketamine, stimulants) and to report co-morbid ADHD, PTSD, ASD, and substance misuse. Participants with a diagnosis of anorexia nervosa were less likely to report psychedelic use, while those with an undiagnosed ED were more likely. Qualitative analysis of responses (n = 200) revealed themes of profound transformation, increased connectedness, and new insights into illness following psychedelic experiences. A handful of respondents reported benefits from microdosing. A few respondents reported adverse outcomes in their open-ended comments, including “bad trips” (n = 15) and worsened ED symptoms (n = 8) after psychedelic use. Conclusions These findings provide a unique insight into psychedelic use among individuals with EDs. The results align with emerging evidence suggesting that psychedelics may be beneficial in this population, highlighting the need for further research, including clinical trials, to explore their efficacy and safety.
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spelling doaj-art-b86a1681342b4ccf8526871e00669ad72025-08-20T04:01:47ZengBMCJournal of Eating Disorders2050-29742025-07-0113112310.1186/s40337-025-01328-5Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED surveySarah-Catherine Rodan0Noah Meez1Sophie Lloyd-Hurwitz2Miguel A. Bedoya-Pérez3Anastasia Suraev4Natasha Sommer5Kayla Greenstien6Sarah Maguire7Iain S. McGregor8Lambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, University of SydneyLambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, University of SydneyLambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, University of SydneyLambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, University of SydneyFaculty of Science, School of Psychology, The University of SydneyLambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, University of SydneyFaculty of Medicine and Health, The University of SydneyFaculty of Medicine and Health, Central Clinical School, InsideOut Institute for Eating Disorders, The University of SydneyLambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, University of SydneyAbstract Background There are few effective treatments for eating disorders (EDs), and new interventions are urgently needed. The MEDication and other drugs For Eating Disorders (“MED–FED”) survey investigated the lived experience of adults with EDs regarding their prescription and non-prescription drugs use. Psychedelic drugs were highly rated in this survey for their impact on ED symptoms and general mental health. Here, we provide a more granular analysis of a subset of the data pertaining to psychedelic drug use from this survey. Methods The MED–FED survey recruited adults who self-reported either a clinically diagnosed ED or disordered eating that was currently undiagnosed but causing significant distress. The demographics of recent and lifetime psychedelic users relative to non-users were examined, as well as their use of other prescription and non-prescription drugs, and co-morbid conditions. Qualitative analysis was used to examine themes emerging from open-ended comments around use of psychedelic drugs. Results Of the 5247 participants who completed the survey, 1699/5247 (32.4%) reported lifetime psychedelic use, with 1019/5247 (19.4%) having used in the last 12 months. Typical use involved infrequent consumption, once or twice per year, of psilocybin, LSD, 2-CB, or DMT. Those who reported recent psychedelic use were younger and less likely to currently use prescription drugs or to have been recently hospitalised for their ED. They were more likely to use other non-prescription drugs (e.g. cannabis, ketamine, stimulants) and to report co-morbid ADHD, PTSD, ASD, and substance misuse. Participants with a diagnosis of anorexia nervosa were less likely to report psychedelic use, while those with an undiagnosed ED were more likely. Qualitative analysis of responses (n = 200) revealed themes of profound transformation, increased connectedness, and new insights into illness following psychedelic experiences. A handful of respondents reported benefits from microdosing. A few respondents reported adverse outcomes in their open-ended comments, including “bad trips” (n = 15) and worsened ED symptoms (n = 8) after psychedelic use. Conclusions These findings provide a unique insight into psychedelic use among individuals with EDs. The results align with emerging evidence suggesting that psychedelics may be beneficial in this population, highlighting the need for further research, including clinical trials, to explore their efficacy and safety.https://doi.org/10.1186/s40337-025-01328-5Eating disorderPsychedelicAnorexia nervosaBulimia nervosaBinge eating disorderARFID
spellingShingle Sarah-Catherine Rodan
Noah Meez
Sophie Lloyd-Hurwitz
Miguel A. Bedoya-Pérez
Anastasia Suraev
Natasha Sommer
Kayla Greenstien
Sarah Maguire
Iain S. McGregor
Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey
Journal of Eating Disorders
Eating disorder
Psychedelic
Anorexia nervosa
Bulimia nervosa
Binge eating disorder
ARFID
title Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey
title_full Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey
title_fullStr Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey
title_full_unstemmed Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey
title_short Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey
title_sort psychedelic use in individuals living with eating disorders or disordered eating findings from the international med fed survey
topic Eating disorder
Psychedelic
Anorexia nervosa
Bulimia nervosa
Binge eating disorder
ARFID
url https://doi.org/10.1186/s40337-025-01328-5
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