Multi-omics integration reveals immune hallmarks and biomarkers associated with FLT3 inhibitor sensitivity in FLT3-mutated AML

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy characterized by poor clinical outcomes, frequently exacerbated by mutations in the FMS-like tyrosine kinase 3 (FLT3) gene. Although FLT3 inhibitors (FLT3i) have emerged as promising therapeutic agents, the absence of molecular bio...

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Bibliographic Details
Main Authors: Mingming Niu, Ning Wang, Dandan Yang, Lixia Fu, Yang Yang, Long Shen, Hong Wang, Xianfeng Shao
Format: Article
Language:English
Published: Wolters Kluwer Health 2025-06-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000227
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