A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression
Abstract RNA interference (RNAi) and oxidative stress inhibition therapeutic strategies have been extensively utilized in the treatment of osteoarthritis (OA), the most prevalent degenerative joint disease. However, the synergistic effects of these approaches on attenuating OA progression remain lar...
Saved in:
| Main Authors: | Qiuyang Wang, Kai Feng, Guangsheng Wan, Wei Liao, Jing Jin, Peng Wang, Xiaolian Sun, Weijun Wang, Qing Jiang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-01-01
|
| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-024-03046-7 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Lipopolymers as the Basis of Non-Viral Delivery of Therapeutic siRNA Nanoparticles in a Leukemia (MOLM-13) Model
by: Panadda Yotsomnuk, et al.
Published: (2025-01-01) -
A systemically deliverable lipid-conjugated siRNA targeting DUX4 as an facioscapulohumeral muscular dystrophy therapeutic
by: Katelyn Daman, et al.
Published: (2025-09-01) -
The biogenesis, regulation and functions of transitive siRNA in plants
by: Tan Huijun, et al.
Published: (2024-09-01) -
Iron and siRNA co-encapsulated ferritin nanocages induce ferroptosis synergistically for cancer therapy
by: Danni Liu, et al.
Published: (2025-01-01) -
A Facile and Promising Delivery Platform for siRNA to Solid Tumors
by: Qixin Leng, et al.
Published: (2024-11-01)