Prevalence of Hepatitis G Virus in Liver Disease

The prevalence of hepatitis G virus (HGV) in liver disease of non-A, -B, -C viral hepatitis, hepatitis B and hepatitis C was determined. Two of 44 patients (4.5%) with liver injury without any hepatitis A, B or C marker were positive for HGV. One of five cases of hepatocellular carcinoma was positiv...

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Main Authors: Hitoshi Takagi, Satoru Kakizaki, Ken Satoh, Mitsuo Toyoda, Norio Horiguchi, Hisashi Takayama, Daisuke Kanda, Hiroaki Nakajima, Takeshi Ichikawa, Akira Kojima, Yutaka Matsuzaki, Ryuya Shimoda, Tatsuhiko Matsumoto, Mieko Kaneko, Yoshiaki Hashimoto, Takehiko Abe, Takeaki Nagamine, Masatomo Mori
Format: Article
Language:English
Published: Wiley 1999-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1999/624969
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author Hitoshi Takagi
Satoru Kakizaki
Ken Satoh
Mitsuo Toyoda
Norio Horiguchi
Hisashi Takayama
Daisuke Kanda
Hiroaki Nakajima
Takeshi Ichikawa
Akira Kojima
Yutaka Matsuzaki
Ryuya Shimoda
Tatsuhiko Matsumoto
Mieko Kaneko
Yoshiaki Hashimoto
Takehiko Abe
Takeaki Nagamine
Masatomo Mori
author_facet Hitoshi Takagi
Satoru Kakizaki
Ken Satoh
Mitsuo Toyoda
Norio Horiguchi
Hisashi Takayama
Daisuke Kanda
Hiroaki Nakajima
Takeshi Ichikawa
Akira Kojima
Yutaka Matsuzaki
Ryuya Shimoda
Tatsuhiko Matsumoto
Mieko Kaneko
Yoshiaki Hashimoto
Takehiko Abe
Takeaki Nagamine
Masatomo Mori
author_sort Hitoshi Takagi
collection DOAJ
description The prevalence of hepatitis G virus (HGV) in liver disease of non-A, -B, -C viral hepatitis, hepatitis B and hepatitis C was determined. Two of 44 patients (4.5%) with liver injury without any hepatitis A, B or C marker were positive for HGV. One of five cases of hepatocellular carcinoma was positive for HGV. One of three cases with fulminant hepatitis was positive for HGV. This case was negative at the onset of fulminant hepatitis and became positive after plasmapheresis. No patient with acute (n=8) or chronic (n=5) hepatitis or liver cirrhosis (n=8) was positive for HGV in non-A, -B, -C liver disease. One of 30 patients with various HBV-positive liver diseases and nine (17.3) of 52 patients with type C liver disease were positive for HGV. In patients with hepatitis C, four (28.6%) of 14 HGV-co-infected patients were complicated with diabetes mellitus compared with four (10.5%) of 38 single hepatitis C virus (HCV)-infected patients (not significant). In 12 HGV-positive patients, eight of 10 (80%) had a history of blood transfusion. In HCV-positive patients, co-infection with HGV was not a risk factor in patients with diabetes mellitus as a complication. HGV appeared to cause non-A, -B, -C hepatitis rarely, and its main route of infection was blood transfusion.
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spelling doaj-art-b855ac3069974e8f9e4e2dcc522952172025-08-20T03:22:46ZengWileyCanadian Journal of Gastroenterology0835-79001999-01-01131082382610.1155/1999/624969Prevalence of Hepatitis G Virus in Liver DiseaseHitoshi Takagi0Satoru Kakizaki1Ken Satoh2Mitsuo Toyoda3Norio Horiguchi4Hisashi Takayama5Daisuke Kanda6Hiroaki Nakajima7Takeshi Ichikawa8Akira Kojima9Yutaka Matsuzaki10Ryuya Shimoda11Tatsuhiko Matsumoto12Mieko Kaneko13Yoshiaki Hashimoto14Takehiko Abe15Takeaki Nagamine16Masatomo Mori17The First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe First Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanThe prevalence of hepatitis G virus (HGV) in liver disease of non-A, -B, -C viral hepatitis, hepatitis B and hepatitis C was determined. Two of 44 patients (4.5%) with liver injury without any hepatitis A, B or C marker were positive for HGV. One of five cases of hepatocellular carcinoma was positive for HGV. One of three cases with fulminant hepatitis was positive for HGV. This case was negative at the onset of fulminant hepatitis and became positive after plasmapheresis. No patient with acute (n=8) or chronic (n=5) hepatitis or liver cirrhosis (n=8) was positive for HGV in non-A, -B, -C liver disease. One of 30 patients with various HBV-positive liver diseases and nine (17.3) of 52 patients with type C liver disease were positive for HGV. In patients with hepatitis C, four (28.6%) of 14 HGV-co-infected patients were complicated with diabetes mellitus compared with four (10.5%) of 38 single hepatitis C virus (HCV)-infected patients (not significant). In 12 HGV-positive patients, eight of 10 (80%) had a history of blood transfusion. In HCV-positive patients, co-infection with HGV was not a risk factor in patients with diabetes mellitus as a complication. HGV appeared to cause non-A, -B, -C hepatitis rarely, and its main route of infection was blood transfusion.http://dx.doi.org/10.1155/1999/624969
spellingShingle Hitoshi Takagi
Satoru Kakizaki
Ken Satoh
Mitsuo Toyoda
Norio Horiguchi
Hisashi Takayama
Daisuke Kanda
Hiroaki Nakajima
Takeshi Ichikawa
Akira Kojima
Yutaka Matsuzaki
Ryuya Shimoda
Tatsuhiko Matsumoto
Mieko Kaneko
Yoshiaki Hashimoto
Takehiko Abe
Takeaki Nagamine
Masatomo Mori
Prevalence of Hepatitis G Virus in Liver Disease
Canadian Journal of Gastroenterology
title Prevalence of Hepatitis G Virus in Liver Disease
title_full Prevalence of Hepatitis G Virus in Liver Disease
title_fullStr Prevalence of Hepatitis G Virus in Liver Disease
title_full_unstemmed Prevalence of Hepatitis G Virus in Liver Disease
title_short Prevalence of Hepatitis G Virus in Liver Disease
title_sort prevalence of hepatitis g virus in liver disease
url http://dx.doi.org/10.1155/1999/624969
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