In vitro biomimetic models for respiratory diseases: progress in lung organoids and lung-on-a-chip

In vitro biomimetic models for respiratory diseases: progress in lung organoids and lung-on-a-chip

Abstract Respiratory diseases pose a growing global public health challenge due to their rising incidence and mortality. Conventional cellular and animal models fall short in replicating the complex three-dimensional (3D) microenvironments of the lung and are limited by species differences, restrict...

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Bibliographic Details
Main Authors: Xiaochun Zhang, Haolin Liu, Haofeng Cheng, Yuhui Cui, Junli Wang, Qianru Yao, Ping Wang, Yuan Hu, Yu Wang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
Subjects:
Lung organoids
Lung-on-a-Chip
Respiratory tract diseases
Online Access:https://doi.org/10.1186/s13287-025-04500-5
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