Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors
As survival rates of preterm infants have increased due to advances in perinatal care, focus has shifted towards the profound long-term effects of prematurity. An extensive amount of evidence has shown increased susceptibility to chronic illnesses among preterm infants. While the onset of such condi...
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| Format: | Article |
| Language: | English |
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European Respiratory Society
2025-06-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/34/176/240267.full |
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| author | Kishan D. Tsang Gerdien A. Tramper-Stranders Jasper V. Been Angelique K. Hoffmann-Haringsma Irwin K. Reiss Marielle W.H. Pijnenburg Ismé M. De Kleer |
| author_facet | Kishan D. Tsang Gerdien A. Tramper-Stranders Jasper V. Been Angelique K. Hoffmann-Haringsma Irwin K. Reiss Marielle W.H. Pijnenburg Ismé M. De Kleer |
| author_sort | Kishan D. Tsang |
| collection | DOAJ |
| description | As survival rates of preterm infants have increased due to advances in perinatal care, focus has shifted towards the profound long-term effects of prematurity. An extensive amount of evidence has shown increased susceptibility to chronic illnesses among preterm infants. While the onset of such conditions typically emerges during adulthood, their roots trace back to the early stages of life. Much of this interest has been directed towards short- and long-term consequences of extreme and very preterm birth. However, it has become apparent that, despite a limited risk of complications during the neonatal period, the moderate and late preterm population suffers from an increased likelihood of morbidity during the course of life. Considering the higher prevalence of moderate and late preterm births compared to extreme and very preterm births, understanding and investigating their health outcomes is essential to address the broader impact of prematurity. In this review, we will discuss the impact of moderate and late prematurity on lung development, function and how environmental factors impose these individuals to increased risk for respiratory morbidity during the course of life. We describe interventions during early life that may protect the moderate-to-late preterm population from adverse lung development and further deterioration by addressing modifiable risk factors. |
| format | Article |
| id | doaj-art-b84724d1fe344c2bb46a836c60fe7b75 |
| institution | Kabale University |
| issn | 0905-9180 1600-0617 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj-art-b84724d1fe344c2bb46a836c60fe7b752025-08-20T03:30:03ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172025-06-013417610.1183/16000617.0267-20240267-2024Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factorsKishan D. Tsang0Gerdien A. Tramper-Stranders1Jasper V. Been2Angelique K. Hoffmann-Haringsma3Irwin K. Reiss4Marielle W.H. Pijnenburg5Ismé M. De Kleer6 Department of Paediatrics, Franciscus Gasthuis and Vlietland, Rotterdam, The Netherlands Department of Paediatrics, Franciscus Gasthuis and Vlietland, Rotterdam, The Netherlands Department of Paediatrics, Division of Neonatal and Paediatric Intensive Care, Erasmus University Medical Centre – Sophia Children's Hospital, Rotterdam, The Netherlands Department of Paediatrics, Franciscus Gasthuis and Vlietland, Rotterdam, The Netherlands Department of Paediatrics, Division of Neonatal and Paediatric Intensive Care, Erasmus University Medical Centre – Sophia Children's Hospital, Rotterdam, The Netherlands Department of Paediatrics, Division of Respiratory Medicine and Allergology, Erasmus University Medical Centre – Sophia Children's Hospital, Rotterdam, The Netherlands Department of Paediatrics, Franciscus Gasthuis and Vlietland, Rotterdam, The Netherlands As survival rates of preterm infants have increased due to advances in perinatal care, focus has shifted towards the profound long-term effects of prematurity. An extensive amount of evidence has shown increased susceptibility to chronic illnesses among preterm infants. While the onset of such conditions typically emerges during adulthood, their roots trace back to the early stages of life. Much of this interest has been directed towards short- and long-term consequences of extreme and very preterm birth. However, it has become apparent that, despite a limited risk of complications during the neonatal period, the moderate and late preterm population suffers from an increased likelihood of morbidity during the course of life. Considering the higher prevalence of moderate and late preterm births compared to extreme and very preterm births, understanding and investigating their health outcomes is essential to address the broader impact of prematurity. In this review, we will discuss the impact of moderate and late prematurity on lung development, function and how environmental factors impose these individuals to increased risk for respiratory morbidity during the course of life. We describe interventions during early life that may protect the moderate-to-late preterm population from adverse lung development and further deterioration by addressing modifiable risk factors.http://err.ersjournals.com/content/34/176/240267.full |
| spellingShingle | Kishan D. Tsang Gerdien A. Tramper-Stranders Jasper V. Been Angelique K. Hoffmann-Haringsma Irwin K. Reiss Marielle W.H. Pijnenburg Ismé M. De Kleer Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors European Respiratory Review |
| title | Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors |
| title_full | Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors |
| title_fullStr | Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors |
| title_full_unstemmed | Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors |
| title_short | Moderate-to-late prematurity: understanding respiratory consequences and modifiable risk factors |
| title_sort | moderate to late prematurity understanding respiratory consequences and modifiable risk factors |
| url | http://err.ersjournals.com/content/34/176/240267.full |
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