4D-Printed Magnetic Responsive Bilayer Hydrogel

Despite its widespread application in targeted drug delivery, soft robotics, and smart screens, magnetic hydrogel still faces challenges from lagging mechanical performance to sluggish response times. In this paper, a methodology of in situ generation of magnetic hydrogel based on 3D printing of pol...

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Main Authors: Yangyang Li, Yuanyi Li, Jiawei Cao, Peng Luo, Jianpeng Liu, Lina Ma, Guo-Lin Gao, Zaixing Jiang
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Nanomaterials
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Online Access:https://www.mdpi.com/2079-4991/15/2/134
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author Yangyang Li
Yuanyi Li
Jiawei Cao
Peng Luo
Jianpeng Liu
Lina Ma
Guo-Lin Gao
Zaixing Jiang
author_facet Yangyang Li
Yuanyi Li
Jiawei Cao
Peng Luo
Jianpeng Liu
Lina Ma
Guo-Lin Gao
Zaixing Jiang
author_sort Yangyang Li
collection DOAJ
description Despite its widespread application in targeted drug delivery, soft robotics, and smart screens, magnetic hydrogel still faces challenges from lagging mechanical performance to sluggish response times. In this paper, a methodology of in situ generation of magnetic hydrogel based on 3D printing of poly-N-isopropylacrylamide (PNIPAM) is presented. A temperature-responsive PNIPAM hydrogel was prepared by 3D printing, and Fe<sub>2</sub>O<sub>3</sub> magnetic particles were generated in situ within the PNIPAM network to generate the magnetic hydrogel. By forming uniformly distributed magnetic particles in situ within the polymer network, 3D printing of customized magnetic hydrogel materials was successfully achieved. The bilayer hydrogel structure was designed according to the different swelling ratios of temperature-sensitive hydrogel and magnetic hydrogel. Combined with the excellent mechanical properties of PNIPAM and printable magnetic hydrogel, 4D-printed remote magnetic field triggered shape morphing of bilayers of five-petal flower-shaped hydrogels was presented, and the deformation process was finished within 300 s.
format Article
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institution Kabale University
issn 2079-4991
language English
publishDate 2025-01-01
publisher MDPI AG
record_format Article
series Nanomaterials
spelling doaj-art-b84096b838514f1c90809772ed36bd6e2025-01-24T13:44:16ZengMDPI AGNanomaterials2079-49912025-01-0115213410.3390/nano150201344D-Printed Magnetic Responsive Bilayer HydrogelYangyang Li0Yuanyi Li1Jiawei Cao2Peng Luo3Jianpeng Liu4Lina Ma5Guo-Lin Gao6Zaixing Jiang7MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, ChinaMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, ChinaMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, ChinaJianghuai Advance Technology Center, Hefei 230009, ChinaJianghuai Advance Technology Center, Hefei 230009, ChinaCollege of Chemistry and Chemical Engineering, Qingdao University, Qingdao 266071, ChinaMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, ChinaMIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, ChinaDespite its widespread application in targeted drug delivery, soft robotics, and smart screens, magnetic hydrogel still faces challenges from lagging mechanical performance to sluggish response times. In this paper, a methodology of in situ generation of magnetic hydrogel based on 3D printing of poly-N-isopropylacrylamide (PNIPAM) is presented. A temperature-responsive PNIPAM hydrogel was prepared by 3D printing, and Fe<sub>2</sub>O<sub>3</sub> magnetic particles were generated in situ within the PNIPAM network to generate the magnetic hydrogel. By forming uniformly distributed magnetic particles in situ within the polymer network, 3D printing of customized magnetic hydrogel materials was successfully achieved. The bilayer hydrogel structure was designed according to the different swelling ratios of temperature-sensitive hydrogel and magnetic hydrogel. Combined with the excellent mechanical properties of PNIPAM and printable magnetic hydrogel, 4D-printed remote magnetic field triggered shape morphing of bilayers of five-petal flower-shaped hydrogels was presented, and the deformation process was finished within 300 s.https://www.mdpi.com/2079-4991/15/2/134intelligent hydrogelmagnetic responsive gels4D printing
spellingShingle Yangyang Li
Yuanyi Li
Jiawei Cao
Peng Luo
Jianpeng Liu
Lina Ma
Guo-Lin Gao
Zaixing Jiang
4D-Printed Magnetic Responsive Bilayer Hydrogel
Nanomaterials
intelligent hydrogel
magnetic responsive gels
4D printing
title 4D-Printed Magnetic Responsive Bilayer Hydrogel
title_full 4D-Printed Magnetic Responsive Bilayer Hydrogel
title_fullStr 4D-Printed Magnetic Responsive Bilayer Hydrogel
title_full_unstemmed 4D-Printed Magnetic Responsive Bilayer Hydrogel
title_short 4D-Printed Magnetic Responsive Bilayer Hydrogel
title_sort 4d printed magnetic responsive bilayer hydrogel
topic intelligent hydrogel
magnetic responsive gels
4D printing
url https://www.mdpi.com/2079-4991/15/2/134
work_keys_str_mv AT yangyangli 4dprintedmagneticresponsivebilayerhydrogel
AT yuanyili 4dprintedmagneticresponsivebilayerhydrogel
AT jiaweicao 4dprintedmagneticresponsivebilayerhydrogel
AT pengluo 4dprintedmagneticresponsivebilayerhydrogel
AT jianpengliu 4dprintedmagneticresponsivebilayerhydrogel
AT linama 4dprintedmagneticresponsivebilayerhydrogel
AT guolingao 4dprintedmagneticresponsivebilayerhydrogel
AT zaixingjiang 4dprintedmagneticresponsivebilayerhydrogel