Bioactive Self‐Assembled Nanoregulator Enhances Hematoma Resolution and Inhibits Neuroinflammation in the Treatment of Intracerebral Hemorrhage

Bioactive Self‐Assembled Nanoregulator Enhances Hematoma Resolution and Inhibits Neuroinflammation in the Treatment of Intracerebral Hemorrhage

Abstract Hematoma and secondary neuroinflammation continue to pose a significant challenge in the clinical treatment of intracerebral hemorrhage (ICH). This study describes a nanoregulator formed through the self‐assembly of Mg2+ and signal regulatory protein α (SIRPα) DNAzyme (SDz), aimed at enhanc...

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Bibliographic Details
Main Authors: Wenyan Yu, Chengyuan Che, Yi Yang, Yuzhen Zhao, Junjie Liu, Aibing Chen, Jinjin Shi
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Advanced Science
Subjects:
drug delivery
hematoma clearance
intracerebral hemorrhage therapy
microglia polarization
nanotechnology
Online Access:https://doi.org/10.1002/advs.202408647
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