Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital Experience
COVID-19 has been associated with profound hematologic disease processes, including cold agglutinin disease (CAD). We discuss a patient with preexisting stable CAD that was exacerbated by COVID-19. Management of this patient was complicated by the fact that rituximab, a known therapy for CAD, could...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2024-01-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.0133 |
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| _version_ | 1850148115293667328 |
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| author | Jackson Musuuza Gilbert-Roy Kamoga Neelima Gonugunta Janani Baskaran |
| author_facet | Jackson Musuuza Gilbert-Roy Kamoga Neelima Gonugunta Janani Baskaran |
| author_sort | Jackson Musuuza |
| collection | DOAJ |
| description | COVID-19 has been associated with profound hematologic disease processes, including cold agglutinin disease (CAD). We discuss a patient with preexisting stable CAD that was exacerbated by COVID-19. Management of this patient was complicated by the fact that rituximab, a known therapy for CAD, could not be used. Recent reports have shown poorer survival for patients with COVID-19 who received rituximab. In this report, we discuss the pathogenesis of CAD and its management in the context of SARS-CoV-2 infection. We aim to increase awareness of possible exacerbation of CAD by SARS-CoV-2 infection. |
| format | Article |
| id | doaj-art-b8242849e4724804a7d2cf18778be342 |
| institution | OA Journals |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-b8242849e4724804a7d2cf18778be3422025-08-20T02:27:20ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-01-013110.7326/aimcc.2023.0133Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital ExperienceJackson Musuuza0Gilbert-Roy Kamoga1Neelima Gonugunta2Janani Baskaran31Department of Internal Medicine, White River Health, Batesville, Arkansas1Department of Internal Medicine, White River Health, Batesville, Arkansas1Department of Internal Medicine, White River Health, Batesville, Arkansas1Department of Internal Medicine, White River Health, Batesville, ArkansasCOVID-19 has been associated with profound hematologic disease processes, including cold agglutinin disease (CAD). We discuss a patient with preexisting stable CAD that was exacerbated by COVID-19. Management of this patient was complicated by the fact that rituximab, a known therapy for CAD, could not be used. Recent reports have shown poorer survival for patients with COVID-19 who received rituximab. In this report, we discuss the pathogenesis of CAD and its management in the context of SARS-CoV-2 infection. We aim to increase awareness of possible exacerbation of CAD by SARS-CoV-2 infection.https://www.acpjournals.org/doi/10.7326/aimcc.2023.0133 |
| spellingShingle | Jackson Musuuza Gilbert-Roy Kamoga Neelima Gonugunta Janani Baskaran Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital Experience Annals of Internal Medicine: Clinical Cases |
| title | Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital Experience |
| title_full | Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital Experience |
| title_fullStr | Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital Experience |
| title_full_unstemmed | Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital Experience |
| title_short | Acute Exacerbation of Cold Agglutinin Disease by SARS-CoV-2 Infection: A Rural U.S. Hospital Experience |
| title_sort | acute exacerbation of cold agglutinin disease by sars cov 2 infection a rural u s hospital experience |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2023.0133 |
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