Role of the prostaglandin E2 EP1 receptor in traumatic brain injury.
Brain injuries promote upregulation of so-called proinflammatory prostaglandins, notably prostaglandin E2 (PGE2), leading to overactivation of a class of its cognate G-protein-coupled receptors, including EP1, which is considered a promising target for treatment of ischemic stroke. However, the role...
Saved in:
| Main Authors: | Alexander V Glushakov, Jawad A Fazal, Shuh Narumiya, Sylvain Doré |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113689&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Prostaglandin E2 receptor EP4 activation induces tolerogenic dendritic cells to mitigate ischemic acute kidney injury
by: Chunyao Li, et al.
Published: (2025-05-01) -
The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation.
by: Xiaowei Wang, et al.
Published: (2016-08-01) -
Prostaglandin E Receptor Subtype 4 Signaling in the Heart: Role in Ischemia/Reperfusion Injury and Cardiac Hypertrophy
by: Lei Pang, et al.
Published: (2016-01-01) -
Deciphering the mechanobiology of microglia in traumatic brain injury with advanced microsystems
by: Anthony Procès, et al.
Published: (2025-08-01) -
NMDA receptors antagonists alleviated the acute phase of traumatic brain injury
by: Mehrdad Hajinejad, et al.
Published: (2025-02-01)