Verbal Reasoning Impairment in Parkinson’s Disease
Background. The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson’s disease (PD) and healthy controls (HCs). Methods. The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reaso...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2022/3422578 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850176870430015488 |
|---|---|
| author | Antonina Luca Giulia Donzuso Concetta D’Agate Claudio Terravecchia Calogero Cicero Edoardo Giovanni Mostile Giorgia Sciacca Alessandra Nicoletti Mario Zappia |
| author_facet | Antonina Luca Giulia Donzuso Concetta D’Agate Claudio Terravecchia Calogero Cicero Edoardo Giovanni Mostile Giorgia Sciacca Alessandra Nicoletti Mario Zappia |
| author_sort | Antonina Luca |
| collection | DOAJ |
| description | Background. The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson’s disease (PD) and healthy controls (HCs). Methods. The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets. Results. Eighty-seven PD patients (51 men; mean age 63.8±7.9 years) and 87 HCs (46 men; mean age 63.7±8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3±2.1) than HCs (12.9±1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70–0.98; p=0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70–0.98; p=0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r=0.330; p=0.002). Conclusions. PD patients presented lower VR performance than HCs. |
| format | Article |
| id | doaj-art-b813245bedaf47e5abcb501c4b369bb8 |
| institution | OA Journals |
| issn | 1875-8584 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-b813245bedaf47e5abcb501c4b369bb82025-08-20T02:19:11ZengWileyBehavioural Neurology1875-85842022-01-01202210.1155/2022/3422578Verbal Reasoning Impairment in Parkinson’s DiseaseAntonina Luca0Giulia Donzuso1Concetta D’Agate2Claudio Terravecchia3Calogero Cicero Edoardo4Giovanni Mostile5Giorgia Sciacca6Alessandra Nicoletti7Mario Zappia8Department of MedicalDepartment of MedicalDepartment of MedicalDepartment of MedicalDepartment of MedicalDepartment of MedicalDepartment of MedicalDepartment of MedicalDepartment of MedicalBackground. The aim of this study was to assess verbal reasoning (VR) functioning in patients with Parkinson’s disease (PD) and healthy controls (HCs). Methods. The non-demented PD patients and HCs matched by age and global cognition were enrolled in this study. VR was assessed with the verbal reasoning test (VRT), total score, and subsets. Results. Eighty-seven PD patients (51 men; mean age 63.8±7.9 years) and 87 HCs (46 men; mean age 63.7±8.0 years) were enrolled. At univariate analysis, PD patients presented a significantly lower score in the VRT subset classification (12.3±2.1) than HCs (12.9±1.7) with an odds ratio (OR) of 0.8 (95% confidence interval [CI] 0.70–0.98; p=0.003). The strength of association was also confirmed at multivariate analysis (OR = 0.8, 95% CI 0.70–0.98; p=0.003). Moreover, in PD patients, a statistically significant positive correlation was found between VRT-classification and MoCA scores (r=0.330; p=0.002). Conclusions. PD patients presented lower VR performance than HCs.http://dx.doi.org/10.1155/2022/3422578 |
| spellingShingle | Antonina Luca Giulia Donzuso Concetta D’Agate Claudio Terravecchia Calogero Cicero Edoardo Giovanni Mostile Giorgia Sciacca Alessandra Nicoletti Mario Zappia Verbal Reasoning Impairment in Parkinson’s Disease Behavioural Neurology |
| title | Verbal Reasoning Impairment in Parkinson’s Disease |
| title_full | Verbal Reasoning Impairment in Parkinson’s Disease |
| title_fullStr | Verbal Reasoning Impairment in Parkinson’s Disease |
| title_full_unstemmed | Verbal Reasoning Impairment in Parkinson’s Disease |
| title_short | Verbal Reasoning Impairment in Parkinson’s Disease |
| title_sort | verbal reasoning impairment in parkinson s disease |
| url | http://dx.doi.org/10.1155/2022/3422578 |
| work_keys_str_mv | AT antoninaluca verbalreasoningimpairmentinparkinsonsdisease AT giuliadonzuso verbalreasoningimpairmentinparkinsonsdisease AT concettadagate verbalreasoningimpairmentinparkinsonsdisease AT claudioterravecchia verbalreasoningimpairmentinparkinsonsdisease AT calogerociceroedoardo verbalreasoningimpairmentinparkinsonsdisease AT giovannimostile verbalreasoningimpairmentinparkinsonsdisease AT giorgiasciacca verbalreasoningimpairmentinparkinsonsdisease AT alessandranicoletti verbalreasoningimpairmentinparkinsonsdisease AT mariozappia verbalreasoningimpairmentinparkinsonsdisease |