Predictors of a metabolically unhealthy obesity
Over the past 50 years, the number of obese people has increased many times. Despite the excess weight, many patients may be metabolically healthy. But studies show that this condition is an intermediate stage ending with a metabolically unhealthy phenotype, which is associated with an increase in t...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2025-03-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/4212 |
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| author | Yu. V. Burenkov V. I. Shevtsova O. N. Krasnorutskaya Yu. A. Kotova |
| author_facet | Yu. V. Burenkov V. I. Shevtsova O. N. Krasnorutskaya Yu. A. Kotova |
| author_sort | Yu. V. Burenkov |
| collection | DOAJ |
| description | Over the past 50 years, the number of obese people has increased many times. Despite the excess weight, many patients may be metabolically healthy. But studies show that this condition is an intermediate stage ending with a metabolically unhealthy phenotype, which is associated with an increase in the incidence of cardiovascular events. The concept of metabolically unhealthy obesity is characterized by altered levels of various biomarkers, the significance of which in the context of predicting a metabolically unhealthy phenotype remains to be studied. The review is devoted to the analysis of modern research data on the role of hyperuricemia, gut microbiota and its metabolites, adipocytokines, as well as an assessment of their relationship with a metabolically unhealthy obesity. |
| format | Article |
| id | doaj-art-b80e77ff4e704d6fa0d927e10bc73cf1 |
| institution | DOAJ |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2025-03-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-b80e77ff4e704d6fa0d927e10bc73cf12025-08-20T02:59:14Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252025-03-0124210.15829/1728-8800-2025-42123179Predictors of a metabolically unhealthy obesityYu. V. Burenkov0V. I. Shevtsova1O. N. Krasnorutskaya2Yu. A. Kotova3Burdenko Voronezh State Medical UniversityBurdenko Voronezh State Medical UniversityBurdenko Voronezh State Medical UniversityBurdenko Voronezh State Medical UniversityOver the past 50 years, the number of obese people has increased many times. Despite the excess weight, many patients may be metabolically healthy. But studies show that this condition is an intermediate stage ending with a metabolically unhealthy phenotype, which is associated with an increase in the incidence of cardiovascular events. The concept of metabolically unhealthy obesity is characterized by altered levels of various biomarkers, the significance of which in the context of predicting a metabolically unhealthy phenotype remains to be studied. The review is devoted to the analysis of modern research data on the role of hyperuricemia, gut microbiota and its metabolites, adipocytokines, as well as an assessment of their relationship with a metabolically unhealthy obesity.https://cardiovascular.elpub.ru/jour/article/view/4212obesityobesity phenotypesmetabolically unhealthy obesityhyperuricemiamicrobiotametabolitesadipokines |
| spellingShingle | Yu. V. Burenkov V. I. Shevtsova O. N. Krasnorutskaya Yu. A. Kotova Predictors of a metabolically unhealthy obesity Кардиоваскулярная терапия и профилактика obesity obesity phenotypes metabolically unhealthy obesity hyperuricemia microbiota metabolites adipokines |
| title | Predictors of a metabolically unhealthy obesity |
| title_full | Predictors of a metabolically unhealthy obesity |
| title_fullStr | Predictors of a metabolically unhealthy obesity |
| title_full_unstemmed | Predictors of a metabolically unhealthy obesity |
| title_short | Predictors of a metabolically unhealthy obesity |
| title_sort | predictors of a metabolically unhealthy obesity |
| topic | obesity obesity phenotypes metabolically unhealthy obesity hyperuricemia microbiota metabolites adipokines |
| url | https://cardiovascular.elpub.ru/jour/article/view/4212 |
| work_keys_str_mv | AT yuvburenkov predictorsofametabolicallyunhealthyobesity AT vishevtsova predictorsofametabolicallyunhealthyobesity AT onkrasnorutskaya predictorsofametabolicallyunhealthyobesity AT yuakotova predictorsofametabolicallyunhealthyobesity |