Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future Directions

Transcatheter left atrial appendage closure has emerged as a non-pharmacological alternative to long-term anticoagulation for stroke prevention in appropriately selected patients with AF. In this concise review article, the Food and Drug Administration-approved and some other left atrial appendage c...

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Main Author: Chirag Bavishi
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-05-01
Series:US Cardiology Review
Online Access:https://www.uscjournal.com/articleindex/usc.2022.37
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author Chirag Bavishi
author_facet Chirag Bavishi
author_sort Chirag Bavishi
collection DOAJ
description Transcatheter left atrial appendage closure has emerged as a non-pharmacological alternative to long-term anticoagulation for stroke prevention in appropriately selected patients with AF. In this concise review article, the Food and Drug Administration-approved and some other left atrial appendage closure devices that are under investigation are discussed. Currently, Watchman Flx and Amplatzer Amulet are the only two devices that have been approved for commercial use by the Food and Drug Administration. A brief overview of device designs, clinical data on efficacy and safety, major limitations of left atrial appendage closure devices, and perspectives on future direction are provided. The current generation of devices is effective; however, efforts should continue on innovations and refinement of device technology.
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spelling doaj-art-b806a320d61a489998b57bbc21bc96132025-08-20T02:39:23ZengRadcliffe Medical MediaUS Cardiology Review1758-38961758-390X2023-05-011710.15420/usc.2022.37Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future DirectionsChirag Bavishi0Division of Cardiology, University of Missouri School of Medicine, Columbia, MOTranscatheter left atrial appendage closure has emerged as a non-pharmacological alternative to long-term anticoagulation for stroke prevention in appropriately selected patients with AF. In this concise review article, the Food and Drug Administration-approved and some other left atrial appendage closure devices that are under investigation are discussed. Currently, Watchman Flx and Amplatzer Amulet are the only two devices that have been approved for commercial use by the Food and Drug Administration. A brief overview of device designs, clinical data on efficacy and safety, major limitations of left atrial appendage closure devices, and perspectives on future direction are provided. The current generation of devices is effective; however, efforts should continue on innovations and refinement of device technology.https://www.uscjournal.com/articleindex/usc.2022.37
spellingShingle Chirag Bavishi
Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future Directions
US Cardiology Review
title Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future Directions
title_full Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future Directions
title_fullStr Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future Directions
title_full_unstemmed Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future Directions
title_short Transcatheter Left Atrial Appendage Closure: Devices Available, Pitfalls, Advantages, and Future Directions
title_sort transcatheter left atrial appendage closure devices available pitfalls advantages and future directions
url https://www.uscjournal.com/articleindex/usc.2022.37
work_keys_str_mv AT chiragbavishi transcatheterleftatrialappendageclosuredevicesavailablepitfallsadvantagesandfuturedirections