Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis
The objective of this paper is to provide readers with current developments of intra-articular drug delivery systems. In recent years, although the search for a clinically successful ideal carrier is ongoing, sustained-release systems, such as polymeric micro- and nanoparticles, liposomes, and hydro...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Nanotechnology |
| Online Access: | http://dx.doi.org/10.1155/2012/748909 |
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| _version_ | 1832551073577959424 |
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| author | Zhiyue Zhang Guihua Huang |
| author_facet | Zhiyue Zhang Guihua Huang |
| author_sort | Zhiyue Zhang |
| collection | DOAJ |
| description | The objective of this paper is to provide readers with current developments of intra-articular drug delivery systems. In recent years, although the search for a clinically successful ideal carrier is ongoing, sustained-release systems, such as polymeric micro- and nanoparticles, liposomes, and hydrogels, are being extensively studied for intra-articular drug delivery purposes. The advantages associated with long-acting preparations include a longer effect of the drug in the action site and a reduced risk of infection due to numerous injections consequently. This paper discusses the recent developments in the field of intra-articular sustained-release delivery systems for the treatment of osteoarthritis. |
| format | Article |
| id | doaj-art-b7f671a7314f400a9632ad890d61ea07 |
| institution | Kabale University |
| issn | 1687-9503 1687-9511 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Nanotechnology |
| spelling | doaj-art-b7f671a7314f400a9632ad890d61ea072025-02-03T06:05:08ZengWileyJournal of Nanotechnology1687-95031687-95112012-01-01201210.1155/2012/748909748909Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of OsteoarthritisZhiyue Zhang0Guihua Huang1School of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, ChinaSchool of Pharmaceutical Sciences, Shandong University, 44 West Wenhua Road, Jinan, Shandong 250012, ChinaThe objective of this paper is to provide readers with current developments of intra-articular drug delivery systems. In recent years, although the search for a clinically successful ideal carrier is ongoing, sustained-release systems, such as polymeric micro- and nanoparticles, liposomes, and hydrogels, are being extensively studied for intra-articular drug delivery purposes. The advantages associated with long-acting preparations include a longer effect of the drug in the action site and a reduced risk of infection due to numerous injections consequently. This paper discusses the recent developments in the field of intra-articular sustained-release delivery systems for the treatment of osteoarthritis.http://dx.doi.org/10.1155/2012/748909 |
| spellingShingle | Zhiyue Zhang Guihua Huang Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis Journal of Nanotechnology |
| title | Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis |
| title_full | Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis |
| title_fullStr | Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis |
| title_full_unstemmed | Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis |
| title_short | Micro- and Nano-Carrier Mediated Intra-Articular Drug Delivery Systems for the Treatment of Osteoarthritis |
| title_sort | micro and nano carrier mediated intra articular drug delivery systems for the treatment of osteoarthritis |
| url | http://dx.doi.org/10.1155/2012/748909 |
| work_keys_str_mv | AT zhiyuezhang microandnanocarriermediatedintraarticulardrugdeliverysystemsforthetreatmentofosteoarthritis AT guihuahuang microandnanocarriermediatedintraarticulardrugdeliverysystemsforthetreatmentofosteoarthritis |