Primary renal mucosa-associated lymphoid tissue lymphoma coexisting with immune thrombocytopenia
Abstract Background Primary renal mucosa-associated lymphoid tissue (MALT) lymphoma is exceedingly rare. Although immune thrombocytopenia (ITP) may accompany lymphoproliferative disorders, its association with primary renal MALT lymphoma has not been previously reported. Case presentation A 60-year-...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | World Journal of Surgical Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12957-025-03916-w |
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| Summary: | Abstract Background Primary renal mucosa-associated lymphoid tissue (MALT) lymphoma is exceedingly rare. Although immune thrombocytopenia (ITP) may accompany lymphoproliferative disorders, its association with primary renal MALT lymphoma has not been previously reported. Case presentation A 60-year-old male presenting with isolated thrombocytopenia was diagnosed with ITP during hematologic evaluation. Abdominal imaging incidentally revealed an 8.7 × 5.6 cm renal mass. Glucocorticoid therapy successfully stabilized platelet counts, enabling nephroureterectomy. Histopathological analysis demonstrated dense small lymphocyte infiltrates, with immunohistochemical confirmation of CD20 and Bcl-2 positivity establishing a diagnosis of MALT lymphoma. At six-month follow-up, the patient maintained disease-free status without adjuvant therapy. Conclusions We report a rare case of concurrent primary renal MALT lymphoma and ITP, achieving sustained remission through glucocorticoid therapy and surgical resection. |
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| ISSN: | 1477-7819 |