Deciphering alternative splicing patterns during cell fate transition of fast chemical reprogramming

Deciphering alternative splicing patterns during cell fate transition of fast chemical reprogramming

Abstract Background Alternative splicing (AS) is a substantial contributor to the high complexity of transcriptomes in multicellular eukaryotes. Fast chemical reprogramming (FCR) system is an innovative approach that facilitates the rapid transition of somatic cells into induced pluripotent stem cel...

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Bibliographic Details
Main Authors: Yunkun Lu, Kainan Lin, Yeling Ruan, Junjie Li, Huizhen Zhang, Tianyuan Pan, Qianqian Wang, Lianyu Lin, Sijie Feng
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Biology
Subjects:
Alternative splicing
Fast chemical reprogramming
Cell fate transition
Diapause-like state
Online Access:https://doi.org/10.1186/s12915-025-02264-1
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