Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil
Abstract Our study aims to investigate the production of nanocapsules containing chamomile essential oil and assess their antifungal properties. We have developed a technological process for producing nanocapsules, selected chamomile raw materials, extracted the essential oil, and conducted research...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-08802-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849335237710970880 |
|---|---|
| author | Tianjiao Liu Xinyao Qu Mojiao Zhao Dafang Zhang Jianpeng Guo |
| author_facet | Tianjiao Liu Xinyao Qu Mojiao Zhao Dafang Zhang Jianpeng Guo |
| author_sort | Tianjiao Liu |
| collection | DOAJ |
| description | Abstract Our study aims to investigate the production of nanocapsules containing chamomile essential oil and assess their antifungal properties. We have developed a technological process for producing nanocapsules, selected chamomile raw materials, extracted the essential oil, and conducted research on the antimicrobial activity of nanocapsules against four fungal cultures: Candida albicans CGMCC 2.538, Aspergillus fumigatus CGMCC 3.5925, Trichophyton rubrum CGMCC 3.3777 and Epidermophyton floccosum CGMCC 3.3722. Our research revealed significant antimicrobial activity of chamomile-containing nanocapsules against all tested fungi. The zones of fungal inhibition varied depending on the oil concentration and were statistically significant (P < 0.05). The obtained results hold practical significance for the development of antimicrobial agents based on plant oils in the treatment of fungal infections. Further research may focus on the molecular mechanisms of chamomile oil’s action, clinical trials in humans, and the optimization of nanocapsule formulations. These steps may contribute to the development of more effective and targeted antimicrobial agents for combating fungal infections and improving patient health. |
| format | Article |
| id | doaj-art-b7eed9b850aa4170ae0293025fd5ca18 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-b7eed9b850aa4170ae0293025fd5ca182025-08-20T03:45:20ZengNature PortfolioScientific Reports2045-23222025-07-0115111010.1038/s41598-025-08802-9Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oilTianjiao Liu0Xinyao Qu1Mojiao Zhao2Dafang Zhang3Jianpeng Guo4Department of Chinese Medicine and Health Care, Changchun Humanities and Sciences CollegeDepartment of Drug Clinical Trial, The Affiliated Hospital to Changchun University of Chinese MedicineDepartment of Chinese Medicine and Health Care, Changchun Humanities and Sciences CollegeDepartment of Chinese Medicine and Health Care, Changchun Humanities and Sciences CollegeCollege of Pharmacy, Yanbian UniversityAbstract Our study aims to investigate the production of nanocapsules containing chamomile essential oil and assess their antifungal properties. We have developed a technological process for producing nanocapsules, selected chamomile raw materials, extracted the essential oil, and conducted research on the antimicrobial activity of nanocapsules against four fungal cultures: Candida albicans CGMCC 2.538, Aspergillus fumigatus CGMCC 3.5925, Trichophyton rubrum CGMCC 3.3777 and Epidermophyton floccosum CGMCC 3.3722. Our research revealed significant antimicrobial activity of chamomile-containing nanocapsules against all tested fungi. The zones of fungal inhibition varied depending on the oil concentration and were statistically significant (P < 0.05). The obtained results hold practical significance for the development of antimicrobial agents based on plant oils in the treatment of fungal infections. Further research may focus on the molecular mechanisms of chamomile oil’s action, clinical trials in humans, and the optimization of nanocapsule formulations. These steps may contribute to the development of more effective and targeted antimicrobial agents for combating fungal infections and improving patient health.https://doi.org/10.1038/s41598-025-08802-9Antifungal activityAntimicrobial propertiesFungal infectionsPhytotherapyDermatophytes |
| spellingShingle | Tianjiao Liu Xinyao Qu Mojiao Zhao Dafang Zhang Jianpeng Guo Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil Scientific Reports Antifungal activity Antimicrobial properties Fungal infections Phytotherapy Dermatophytes |
| title | Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil |
| title_full | Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil |
| title_fullStr | Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil |
| title_full_unstemmed | Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil |
| title_short | Investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil |
| title_sort | investigation of the production and antifungal properties of nanocapsules containing chamomile essential oil |
| topic | Antifungal activity Antimicrobial properties Fungal infections Phytotherapy Dermatophytes |
| url | https://doi.org/10.1038/s41598-025-08802-9 |
| work_keys_str_mv | AT tianjiaoliu investigationoftheproductionandantifungalpropertiesofnanocapsulescontainingchamomileessentialoil AT xinyaoqu investigationoftheproductionandantifungalpropertiesofnanocapsulescontainingchamomileessentialoil AT mojiaozhao investigationoftheproductionandantifungalpropertiesofnanocapsulescontainingchamomileessentialoil AT dafangzhang investigationoftheproductionandantifungalpropertiesofnanocapsulescontainingchamomileessentialoil AT jianpengguo investigationoftheproductionandantifungalpropertiesofnanocapsulescontainingchamomileessentialoil |