Post-pandemic insights on COVID-19 and premature ovarian insufficiency

The COVID-19 pandemic has raised concerns regarding its potential impact on premature ovarian insufficiency (POI). This overview examines the possible interactions between COVID-19 and POI, while also suggesting preventive measures. The viral infection’s inflammatory response and immune dysregulatio...

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Main Authors: Han Yaguang, Dai Yang, Wang Kexin, Zhang Xin, Shao Zishen, Zhu Xiaolin
Format: Article
Language:English
Published: De Gruyter 2025-01-01
Series:Open Life Sciences
Subjects:
Online Access:https://doi.org/10.1515/biol-2022-1028
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author Han Yaguang
Dai Yang
Wang Kexin
Zhang Xin
Shao Zishen
Zhu Xiaolin
author_facet Han Yaguang
Dai Yang
Wang Kexin
Zhang Xin
Shao Zishen
Zhu Xiaolin
author_sort Han Yaguang
collection DOAJ
description The COVID-19 pandemic has raised concerns regarding its potential impact on premature ovarian insufficiency (POI). This overview examines the possible interactions between COVID-19 and POI, while also suggesting preventive measures. The viral infection’s inflammatory response and immune dysregulation may adversely affect ovarian tissues, leading to inflammation and damage. Additionally, alterations in vascular function could impair ovarian blood flow and hormonal imbalances may disrupt normal ovarian function. Long-term health effects, such as “long COVID,” may exacerbate these issues through chronic inflammation and immune dysfunction. Public health measures, such as vaccination and home isolation, may indirectly protect ovarian health by reducing systemic inflammation. Vaccines could mitigate the severity of COVID-19’s impact on ovarian function, while isolation may reduce stress and inflammation. However, further research is needed to validate these mechanisms.
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language English
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series Open Life Sciences
spelling doaj-art-b7ec826092aa486aa3cb32720eae0b7d2025-02-02T15:44:51ZengDe GruyterOpen Life Sciences2391-54122025-01-012016269248210.1515/biol-2022-1028Post-pandemic insights on COVID-19 and premature ovarian insufficiencyHan Yaguang0Dai Yang1Wang Kexin2Zhang Xin3Shao Zishen4Zhu Xiaolin5Department of Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, ChinaDepartment of Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, ChinaDepartment of Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, ChinaDepartment of Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, ChinaDepartment of Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, 150040, ChinaDepartment of Medicine, Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, No. 411 Guogeli Street, Nangang District, Harbin, Heilongjiang, 150006, P.R. ChinaThe COVID-19 pandemic has raised concerns regarding its potential impact on premature ovarian insufficiency (POI). This overview examines the possible interactions between COVID-19 and POI, while also suggesting preventive measures. The viral infection’s inflammatory response and immune dysregulation may adversely affect ovarian tissues, leading to inflammation and damage. Additionally, alterations in vascular function could impair ovarian blood flow and hormonal imbalances may disrupt normal ovarian function. Long-term health effects, such as “long COVID,” may exacerbate these issues through chronic inflammation and immune dysfunction. Public health measures, such as vaccination and home isolation, may indirectly protect ovarian health by reducing systemic inflammation. Vaccines could mitigate the severity of COVID-19’s impact on ovarian function, while isolation may reduce stress and inflammation. However, further research is needed to validate these mechanisms.https://doi.org/10.1515/biol-2022-1028covid-19premature ovarian insufficiencyimmune dysregulationclinical preventionpublic health
spellingShingle Han Yaguang
Dai Yang
Wang Kexin
Zhang Xin
Shao Zishen
Zhu Xiaolin
Post-pandemic insights on COVID-19 and premature ovarian insufficiency
Open Life Sciences
covid-19
premature ovarian insufficiency
immune dysregulation
clinical prevention
public health
title Post-pandemic insights on COVID-19 and premature ovarian insufficiency
title_full Post-pandemic insights on COVID-19 and premature ovarian insufficiency
title_fullStr Post-pandemic insights on COVID-19 and premature ovarian insufficiency
title_full_unstemmed Post-pandemic insights on COVID-19 and premature ovarian insufficiency
title_short Post-pandemic insights on COVID-19 and premature ovarian insufficiency
title_sort post pandemic insights on covid 19 and premature ovarian insufficiency
topic covid-19
premature ovarian insufficiency
immune dysregulation
clinical prevention
public health
url https://doi.org/10.1515/biol-2022-1028
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AT wangkexin postpandemicinsightsoncovid19andprematureovarianinsufficiency
AT zhangxin postpandemicinsightsoncovid19andprematureovarianinsufficiency
AT shaozishen postpandemicinsightsoncovid19andprematureovarianinsufficiency
AT zhuxiaolin postpandemicinsightsoncovid19andprematureovarianinsufficiency