New approach methodologies for in vitro toxicity screening of nanomaterial using a pulmonary three-dimensional floating extracellular matrix model

New approach methodologies for in vitro toxicity screening of nanomaterial using a pulmonary three-dimensional floating extracellular matrix model

Abstract Background Nanomaterials offer increasing applications across diverse sectors, including food science, medicine, and electronics. Environmental risk assessment is crucial for ensuring the safety and sustainability of nanomaterials. However, high-throughput screening (HTS) of their potential...

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Main Authors: Soojin Kim, Mi-Sun Choi, Hyun Jegal, Min Beom Heo, Minjeong Kwak, Hyun Kyong Shon, Seungwoo Song, Tae Geol Lee, Ji-Ho Park, Dong Woo Lee, Seokjoo Yoon, Jung-Hwa Oh
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Biological Engineering
Subjects:
New approach methodologies
Silica nanoparticles
in vitro cytotoxicity
High-throughput screening
Three-dimensional cell
Extracellular matrix
Online Access:https://doi.org/10.1186/s13036-025-00532-w
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