Atroposelective Synthesis of Biaryl N‐Oxides via Cu‐Catalyzed De Novo Heteroaromatic N‐Oxide Ring Formation
Abstract Heteroaromatic N‐oxides, renowned for their highly polar N─O bond and robust structure, exhibit significant bioactivities and have played a pivotal role in various drug development projects since the discovery of Minoxidil. Moreover, heteroaromatic N‐oxides, featuring axially chiral biaryl...
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| Main Authors: | Ke Ma, Ting Qi, Lei Hu, Chen Chen, Wan Wang, Jun‐Long Li, Cheng Peng, Gu Zhan, Bo Han |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-10-01
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| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202405743 |
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