State of the art: Intrapartum antibiotics in cesarean section, the infant microbiota and allergic diseases

Abstract With increasing rates of cesarean section worldwide and international guidelines advising pre‐incision antibiotics, neonatal exposure to pre‐birth antibiotics is higher than ever before. Emerging evidence has raised concern regarding the impact of such antibiotics on the neonatal intestinal...

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Bibliographic Details
Main Authors: Jassy Moore, Severine Navarro, Kate McCarthy, Ridwan B. Rashid, Simon Phipps, Akwasi Amoako, Leonie Callaway, Victoria Eley
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Acta Obstetricia et Gynecologica Scandinavica
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Online Access:https://doi.org/10.1111/aogs.14577
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Summary:Abstract With increasing rates of cesarean section worldwide and international guidelines advising pre‐incision antibiotics, neonatal exposure to pre‐birth antibiotics is higher than ever before. Emerging evidence has raised concern regarding the impact of such antibiotics on the neonatal intestinal microbiota, immune system development and health conditions later in life. This narrative review investigates current protocols for intrapartum prophylactic antibiotics in cesarean section, how this and other factors may affect the neonatal intestinal microbiota and whether intrapartum antibiotics used for cesarean section are linked to the development of allergic disease.
ISSN:0001-6349
1600-0412