Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients
Despite many advances in the management of patients with colorectal cancer, this malignancy remains the second leading cause of cancer death worldwide. One of the keys to improve the prognosis of these patients is diagnosis in early stages, making them eligible for curative surgical treatment. Cutan...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-01-01
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| Series: | Gastrointestinal Disorders |
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| Online Access: | https://www.mdpi.com/2624-5647/7/1/8 |
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| author | Vlad Alexandru Ionescu Gina Gheorghe Teodor Florin Georgescu Vlad Buica Mihai-Stefan Catanescu Iris-Andreea Cercel Beatrice Budeanu Mihail Budan Ancuta Nastac Ninel Iacobus Antonie Daniel O. Costache Raluca Simona Costache Nicolae Bacalbasa Loredana-Crista Tiuca Camelia Cristina Diaconu |
| author_facet | Vlad Alexandru Ionescu Gina Gheorghe Teodor Florin Georgescu Vlad Buica Mihai-Stefan Catanescu Iris-Andreea Cercel Beatrice Budeanu Mihail Budan Ancuta Nastac Ninel Iacobus Antonie Daniel O. Costache Raluca Simona Costache Nicolae Bacalbasa Loredana-Crista Tiuca Camelia Cristina Diaconu |
| author_sort | Vlad Alexandru Ionescu |
| collection | DOAJ |
| description | Despite many advances in the management of patients with colorectal cancer, this malignancy remains the second leading cause of cancer death worldwide. One of the keys to improve the prognosis of these patients is diagnosis in early stages, making them eligible for curative surgical treatment. Cutaneous paraneoplastic syndromes can enhance the diagnostic management of these patients. The time elapsed from the appearance of skin lesions to the appearance of the first digestive symptoms can reach up to a decade. Thus, comprehensive paraclinical evaluation and the monitoring of patients with specific skin lesions play an important role in detecting an underlying cancer. Given these findings, it is imperative to increase the awareness of cutaneous paraneoplastic syndromes among patients and medical professionals. Additionally, the investigation of the mechanisms that elucidate this pathogenic link has the potential to result in the identification of novel therapeutic targets. |
| format | Article |
| id | doaj-art-b7bd47d40c8b42108d433a40766c68f8 |
| institution | Kabale University |
| issn | 2624-5647 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastrointestinal Disorders |
| spelling | doaj-art-b7bd47d40c8b42108d433a40766c68f82025-08-20T03:43:22ZengMDPI AGGastrointestinal Disorders2624-56472025-01-0171810.3390/gidisord7010008Cutaneous Paraneoplastic Syndromes in Colorectal Cancer PatientsVlad Alexandru Ionescu0Gina Gheorghe1Teodor Florin Georgescu2Vlad Buica3Mihai-Stefan Catanescu4Iris-Andreea Cercel5Beatrice Budeanu6Mihail Budan7Ancuta Nastac8Ninel Iacobus Antonie9Daniel O. Costache10Raluca Simona Costache11Nicolae Bacalbasa12Loredana-Crista Tiuca13Camelia Cristina Diaconu14Faculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy “Carol Davila” Bucharest, 050474 Bucharest, RomaniaDespite many advances in the management of patients with colorectal cancer, this malignancy remains the second leading cause of cancer death worldwide. One of the keys to improve the prognosis of these patients is diagnosis in early stages, making them eligible for curative surgical treatment. Cutaneous paraneoplastic syndromes can enhance the diagnostic management of these patients. The time elapsed from the appearance of skin lesions to the appearance of the first digestive symptoms can reach up to a decade. Thus, comprehensive paraclinical evaluation and the monitoring of patients with specific skin lesions play an important role in detecting an underlying cancer. Given these findings, it is imperative to increase the awareness of cutaneous paraneoplastic syndromes among patients and medical professionals. Additionally, the investigation of the mechanisms that elucidate this pathogenic link has the potential to result in the identification of novel therapeutic targets.https://www.mdpi.com/2624-5647/7/1/8colorectal cancerparaneoplastic cutaneous syndromesdiagnosisscreeningprognosis |
| spellingShingle | Vlad Alexandru Ionescu Gina Gheorghe Teodor Florin Georgescu Vlad Buica Mihai-Stefan Catanescu Iris-Andreea Cercel Beatrice Budeanu Mihail Budan Ancuta Nastac Ninel Iacobus Antonie Daniel O. Costache Raluca Simona Costache Nicolae Bacalbasa Loredana-Crista Tiuca Camelia Cristina Diaconu Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients Gastrointestinal Disorders colorectal cancer paraneoplastic cutaneous syndromes diagnosis screening prognosis |
| title | Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients |
| title_full | Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients |
| title_fullStr | Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients |
| title_full_unstemmed | Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients |
| title_short | Cutaneous Paraneoplastic Syndromes in Colorectal Cancer Patients |
| title_sort | cutaneous paraneoplastic syndromes in colorectal cancer patients |
| topic | colorectal cancer paraneoplastic cutaneous syndromes diagnosis screening prognosis |
| url | https://www.mdpi.com/2624-5647/7/1/8 |
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