Multiple-clone infections of Mpox: Insights from a single primary lesion

Multiple-clone infections of Mpox: Insights from a single primary lesion

Objectives: The 2022 Mpox epidemic transitioned to human-to-human transmission through primary lesions, showing a higher rate of genomic mutations than typical for a DNA virus. While Orthopoxviruses are traditionally considered to cause monoclonal infections in a single patient, we explored whether...

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Bibliographic Details
Main Authors: Natsuko Kaku, Mayo Yasugi, Evariste Tshibangu-Kabamba, Yoshiyuki Wakabayashi, Yuko Uesaka, Yu Nakagama, Takuto Nogimori, Takuya Yamamoto, Placide Mbala-Kingebeni, Dieudonné Mumba Ngoyi, Eisuke Adachi, Yasutoshi Kido
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:CMI Communications
Subjects:
Mpox virus
Multiple-clone infections
Genomic plasticity
Intra-host evolution
Human-to-human transmission
Online Access:http://www.sciencedirect.com/science/article/pii/S295059092405042X
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