Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers

The preparation and performance evaluation of the cyclodextrin bifunctional monomer molecularly imprinted polymer were studied. A series of di (2-ethylhexyl) phthalate (DEHP) imprinted polymers were prepared using allyl-β-cyclodextrin (allyl-β-CD) either alone or in conjunction with methacrylic acid...

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Main Authors: YU Haining, HUANG Haiyong, HE Chengzijing, LAY Sovichea, SHEN Shengrong
Format: Article
Language:English
Published: Zhejiang University Press 2018-11-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2017.09.062
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author YU Haining
HUANG Haiyong
HE Chengzijing
LAY Sovichea
SHEN Shengrong
author_facet YU Haining
HUANG Haiyong
HE Chengzijing
LAY Sovichea
SHEN Shengrong
author_sort YU Haining
collection DOAJ
description The preparation and performance evaluation of the cyclodextrin bifunctional monomer molecularly imprinted polymer were studied. A series of di (2-ethylhexyl) phthalate (DEHP) imprinted polymers were prepared using allyl-β-cyclodextrin (allyl-β-CD) either alone or in conjunction with methacrylic acid (MAA), methyl methacrylate (MMA), acrylonitrile (AN), and acrylamide (AA) as the binary functional monomers. According to values of the binding specificity experiment, the binary functional monomers (M-MAA, M-MMA, and M-AN) were superior to a single functional monomer (M-β-CD); the average value of bound substrates from binary functional monomers was 110 μmol/g, whereas a single was 90 μmol/g. When M-MAA, M-MMA and M-AN were chosen as the stationary phase for molecularly imprinted solid-phase extraction (MISPE) and used to analyze the spiked infant formula, the recovery rate of DEHP ranged from 89.06% to 97.98% with relative standard deviations (RSD)≤6.47%. In addition, computational simulation results showed that MAA and AN had the strongest binding capacity with template molecules. All in all, the productions of binary functional monomer-synthesized molecularly imprinted polymer (MIPs) have yielded higher binding ability than that of single ones and are efficient separation of hydrophobic molecules.
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series 浙江大学学报. 农业与生命科学版
spelling doaj-art-b7b241561e444a3b8143136e06d47bec2025-08-20T03:58:11ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552018-11-014469570310.3785/j.issn.1008-9209.2017.09.06210089209Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymersYU HainingHUANG HaiyongHE ChengzijingLAY SovicheaSHEN ShengrongThe preparation and performance evaluation of the cyclodextrin bifunctional monomer molecularly imprinted polymer were studied. A series of di (2-ethylhexyl) phthalate (DEHP) imprinted polymers were prepared using allyl-β-cyclodextrin (allyl-β-CD) either alone or in conjunction with methacrylic acid (MAA), methyl methacrylate (MMA), acrylonitrile (AN), and acrylamide (AA) as the binary functional monomers. According to values of the binding specificity experiment, the binary functional monomers (M-MAA, M-MMA, and M-AN) were superior to a single functional monomer (M-β-CD); the average value of bound substrates from binary functional monomers was 110 μmol/g, whereas a single was 90 μmol/g. When M-MAA, M-MMA and M-AN were chosen as the stationary phase for molecularly imprinted solid-phase extraction (MISPE) and used to analyze the spiked infant formula, the recovery rate of DEHP ranged from 89.06% to 97.98% with relative standard deviations (RSD)≤6.47%. In addition, computational simulation results showed that MAA and AN had the strongest binding capacity with template molecules. All in all, the productions of binary functional monomer-synthesized molecularly imprinted polymer (MIPs) have yielded higher binding ability than that of single ones and are efficient separation of hydrophobic molecules.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2017.09.062molecularly imprinted polymerssolid-phase extractionphthalatescyclodextrincomputational simulation
spellingShingle YU Haining
HUANG Haiyong
HE Chengzijing
LAY Sovichea
SHEN Shengrong
Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers
浙江大学学报. 农业与生命科学版
molecularly imprinted polymers
solid-phase extraction
phthalates
cyclodextrin
computational simulation
title Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers
title_full Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers
title_fullStr Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers
title_full_unstemmed Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers
title_short Preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers
title_sort preparation and performance evaluation of cyclodextrin bifunctional monomer molecularly imprinted polymers
topic molecularly imprinted polymers
solid-phase extraction
phthalates
cyclodextrin
computational simulation
url https://www.academax.com/doi/10.3785/j.issn.1008-9209.2017.09.062
work_keys_str_mv AT yuhaining preparationandperformanceevaluationofcyclodextrinbifunctionalmonomermolecularlyimprintedpolymers
AT huanghaiyong preparationandperformanceevaluationofcyclodextrinbifunctionalmonomermolecularlyimprintedpolymers
AT hechengzijing preparationandperformanceevaluationofcyclodextrinbifunctionalmonomermolecularlyimprintedpolymers
AT laysovichea preparationandperformanceevaluationofcyclodextrinbifunctionalmonomermolecularlyimprintedpolymers
AT shenshengrong preparationandperformanceevaluationofcyclodextrinbifunctionalmonomermolecularlyimprintedpolymers