On the issue of telocytes of skin
This manuscript is devoted to the description of a new population of interstitial cells – telocytes discovered by L.M. Popescu and M.S. Faussone-Pellegrini. Later telocytes were found in the dermis, where they perform an important metabolic function and maintain homeostasis. Telocytes are small cell...
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| Format: | Article |
| Language: | Russian |
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Private institution educational organization of higher education "Medical University "ReaViz"
2020-12-01
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| Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
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| Online Access: | https://vestnik.reaviz.ru/jour/article/view/91 |
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| _version_ | 1849694486115909632 |
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| author | A. Yu. Tcibulevsky |
| author_facet | A. Yu. Tcibulevsky |
| author_sort | A. Yu. Tcibulevsky |
| collection | DOAJ |
| description | This manuscript is devoted to the description of a new population of interstitial cells – telocytes discovered by L.M. Popescu and M.S. Faussone-Pellegrini. Later telocytes were found in the dermis, where they perform an important metabolic function and maintain homeostasis. Telocytes are small cells with a large elongated nucleus and a small amount of cytoplasm, which contains long cellular prolongations made of thin (podomeres, 40–100 nm) and thick (pods, 200–500 nm) segments – telopodes. Based on the results of morphological studies, it was possible to reliably differentiate telocytes from fibroblasts. During immunostaining they express CD34 and PDGFRα. Nevertheless, despite the numerous studies carried out regarding the role of telocytes, their function in the skin remains unclear and requires further investigations. |
| format | Article |
| id | doaj-art-b7a7bcd1dd5b40e2bb929768ea9ddc7e |
| institution | DOAJ |
| issn | 2226-762X 2782-1579 |
| language | Russian |
| publishDate | 2020-12-01 |
| publisher | Private institution educational organization of higher education "Medical University "ReaViz" |
| record_format | Article |
| series | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
| spelling | doaj-art-b7a7bcd1dd5b40e2bb929768ea9ddc7e2025-08-20T03:20:03ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792020-12-010413513610.20340/vmi-rvz.2020.4.1585On the issue of telocytes of skinA. Yu. Tcibulevsky0Private Institution of Higher Education ‘Moscow Medical University ‘Reaviz’This manuscript is devoted to the description of a new population of interstitial cells – telocytes discovered by L.M. Popescu and M.S. Faussone-Pellegrini. Later telocytes were found in the dermis, where they perform an important metabolic function and maintain homeostasis. Telocytes are small cells with a large elongated nucleus and a small amount of cytoplasm, which contains long cellular prolongations made of thin (podomeres, 40–100 nm) and thick (pods, 200–500 nm) segments – telopodes. Based on the results of morphological studies, it was possible to reliably differentiate telocytes from fibroblasts. During immunostaining they express CD34 and PDGFRα. Nevertheless, despite the numerous studies carried out regarding the role of telocytes, their function in the skin remains unclear and requires further investigations.https://vestnik.reaviz.ru/jour/article/view/91telocytescd34pdgfrαskin |
| spellingShingle | A. Yu. Tcibulevsky On the issue of telocytes of skin Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье telocytes cd34 pdgfrα skin |
| title | On the issue of telocytes of skin |
| title_full | On the issue of telocytes of skin |
| title_fullStr | On the issue of telocytes of skin |
| title_full_unstemmed | On the issue of telocytes of skin |
| title_short | On the issue of telocytes of skin |
| title_sort | on the issue of telocytes of skin |
| topic | telocytes cd34 pdgfrα skin |
| url | https://vestnik.reaviz.ru/jour/article/view/91 |
| work_keys_str_mv | AT ayutcibulevsky ontheissueoftelocytesofskin |