Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination

Abstract Background The increase in the older adult population over the coming decades emphasizes the importance of vaccinations to prevent infectious diseases among this population. Acceptance of vaccination is crucial for a successful vaccination program and insight in the motives of acceptation i...

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Main Authors: Renske Eilers, Fleur H. Groenendijk, Birthe A. Lehman, Nynke Y. Rots, Hester E. de Melker, Liesbeth Mollema, Josine van Beek
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Public Health
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Online Access:https://doi.org/10.1186/s12889-025-22144-1
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author Renske Eilers
Fleur H. Groenendijk
Birthe A. Lehman
Nynke Y. Rots
Hester E. de Melker
Liesbeth Mollema
Josine van Beek
author_facet Renske Eilers
Fleur H. Groenendijk
Birthe A. Lehman
Nynke Y. Rots
Hester E. de Melker
Liesbeth Mollema
Josine van Beek
author_sort Renske Eilers
collection DOAJ
description Abstract Background The increase in the older adult population over the coming decades emphasizes the importance of vaccinations to prevent infectious diseases among this population. Acceptance of vaccination is crucial for a successful vaccination program and insight in the motives of acceptation is therefore important. This study explores specifically the association between experiencing influenza-like illness (ILI) and other determinants for older adults on seasonal influenza vaccination acceptance. Furthermore, differences in acceptance of pneumococcal, influenza, herpes zoster and pertussis vaccines between various age groups were studied. Methods Three prospective observational studies (2011/2012, 2012/2013 and 2014/2015) were performed in community-dwelling older adults (≥ 60 years) to monitor ILI. During home visits, throat/nose swabs, a blood sample and a questionnaire on demographics and general health were collected. An additional questionnaire was added to the 2014/2015 study on motives and intention of older adults to accept seasonal influenza and other vaccinations, including knowledge statements on vaccination in general (n = 1647). Random Forest analyses were used to identify predictors of intention to accept seasonal influenza vaccination. Results Univariate analyses showed that males, persons with limited contact with children, people who have received seasonal influenza vaccination in 2014/2015, persons reporting co-morbidity, persons reporting a lower perceived health and persons with more knowledge about vaccination have a significantly higher intention to accept seasonal influenza vaccination. The univariate and prediction analyses showed no association between having experienced ILI and the intention to receive seasonal influenza vaccination. Previous influenza vaccination had by far the most predictive value; when excluding this factor, age and perceived health were the best predictors. Except for pertussis vaccination, persons aged ≥ 70 years had a higher intention to vaccinate compared to persons aged 60–69 years. Conclusions Our study showed that there is no association between having experienced ILI and the intention to receive seasonal influenza vaccination. Instead, previous influenza vaccination had the highest predictive value. Therefore, efforts should be made to make vaccination a habit to ensure annual vaccination. Healthcare workers, such as general practitioners (GPs) could play an important role in this because of frequent contact between older adults and GPs and the perceived importance of the advice of the GP. Trial registration NTR4818 (30-09-2014).
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spelling doaj-art-b7a3fb01988c4a8fbfcdf5c0f5c750d42025-08-20T02:10:10ZengBMCBMC Public Health1471-24582025-03-0125111210.1186/s12889-025-22144-1Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccinationRenske Eilers0Fleur H. Groenendijk1Birthe A. Lehman2Nynke Y. Rots3Hester E. de Melker4Liesbeth Mollema5Josine van Beek6Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM)Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM)Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM)Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM)Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM)Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM)Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM)Abstract Background The increase in the older adult population over the coming decades emphasizes the importance of vaccinations to prevent infectious diseases among this population. Acceptance of vaccination is crucial for a successful vaccination program and insight in the motives of acceptation is therefore important. This study explores specifically the association between experiencing influenza-like illness (ILI) and other determinants for older adults on seasonal influenza vaccination acceptance. Furthermore, differences in acceptance of pneumococcal, influenza, herpes zoster and pertussis vaccines between various age groups were studied. Methods Three prospective observational studies (2011/2012, 2012/2013 and 2014/2015) were performed in community-dwelling older adults (≥ 60 years) to monitor ILI. During home visits, throat/nose swabs, a blood sample and a questionnaire on demographics and general health were collected. An additional questionnaire was added to the 2014/2015 study on motives and intention of older adults to accept seasonal influenza and other vaccinations, including knowledge statements on vaccination in general (n = 1647). Random Forest analyses were used to identify predictors of intention to accept seasonal influenza vaccination. Results Univariate analyses showed that males, persons with limited contact with children, people who have received seasonal influenza vaccination in 2014/2015, persons reporting co-morbidity, persons reporting a lower perceived health and persons with more knowledge about vaccination have a significantly higher intention to accept seasonal influenza vaccination. The univariate and prediction analyses showed no association between having experienced ILI and the intention to receive seasonal influenza vaccination. Previous influenza vaccination had by far the most predictive value; when excluding this factor, age and perceived health were the best predictors. Except for pertussis vaccination, persons aged ≥ 70 years had a higher intention to vaccinate compared to persons aged 60–69 years. Conclusions Our study showed that there is no association between having experienced ILI and the intention to receive seasonal influenza vaccination. Instead, previous influenza vaccination had the highest predictive value. Therefore, efforts should be made to make vaccination a habit to ensure annual vaccination. Healthcare workers, such as general practitioners (GPs) could play an important role in this because of frequent contact between older adults and GPs and the perceived importance of the advice of the GP. Trial registration NTR4818 (30-09-2014).https://doi.org/10.1186/s12889-025-22144-1Vaccine acceptanceDeterminantsInfluenza vaccinationInfluenza-like illness
spellingShingle Renske Eilers
Fleur H. Groenendijk
Birthe A. Lehman
Nynke Y. Rots
Hester E. de Melker
Liesbeth Mollema
Josine van Beek
Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination
BMC Public Health
Vaccine acceptance
Determinants
Influenza vaccination
Influenza-like illness
title Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination
title_full Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination
title_fullStr Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination
title_full_unstemmed Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination
title_short Influence of perceived influenza-like symptoms on intention to receive seasonal influenza vaccination
title_sort influence of perceived influenza like symptoms on intention to receive seasonal influenza vaccination
topic Vaccine acceptance
Determinants
Influenza vaccination
Influenza-like illness
url https://doi.org/10.1186/s12889-025-22144-1
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