Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.

The application of the organophosphate larvicide temephos to water storage containers is one of the most commonly employed dengue vector control methods. This systematic literature review is to the knowledge of the authors the first that aims to assess the community-effectiveness of temephos in cont...

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Main Authors: Leyanna George, Audrey Lenhart, Joao Toledo, Adhara Lazaro, Wai Wai Han, Raman Velayudhan, Silvia Runge Ranzinger, Olaf Horstick
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0004006
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author Leyanna George
Audrey Lenhart
Joao Toledo
Adhara Lazaro
Wai Wai Han
Raman Velayudhan
Silvia Runge Ranzinger
Olaf Horstick
author_facet Leyanna George
Audrey Lenhart
Joao Toledo
Adhara Lazaro
Wai Wai Han
Raman Velayudhan
Silvia Runge Ranzinger
Olaf Horstick
author_sort Leyanna George
collection DOAJ
description The application of the organophosphate larvicide temephos to water storage containers is one of the most commonly employed dengue vector control methods. This systematic literature review is to the knowledge of the authors the first that aims to assess the community-effectiveness of temephos in controlling both vectors and dengue transmission when delivered either as a single intervention or in combination with other interventions. A comprehensive literature search of 6 databases was performed (PubMed, WHOLIS, GIFT, CDSR, EMBASE, Wiley), grey literature and cross references were also screened for relevant studies. Data were extracted and methodological quality of the studies was assessed independently by two reviewers. 27 studies were included in this systematic review (11 single intervention studies and 16 combined intervention studies). All 11 single intervention studies showed consistently that using temephos led to a reduction in entomological indices. Although 11 of the 16 combined intervention studies showed that temephos application together with other chemical vector control methods also reduced entomological indices, this was either not sustained over time or-as in the five remaining studies--failed to reduce the immature stages. The community-effectiveness of temephos was found to be dependent on factors such as quality of delivery, water turnover rate, type of water, and environmental factors such as organic debris, temperature and exposure to sunlight. Timing of temephos deployment and its need for reapplication, along with behavioural factors such as the reluctance of its application to drinking water, and operational aspects such as cost, supplies, time and labour were further limitations identified in this review. In conclusion, when applied as a single intervention, temephos was found to be effective at suppressing entomological indices, however, the same effect has not been observed when temephos was applied in combination with other interventions. There is no evidence to suggest that temephos use is associated with reductions in dengue transmission.
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spelling doaj-art-b7a2169ebcf4449fbab1572a518e2ebe2025-08-20T02:37:03ZengPublic Library of Science (PLoS)PLoS Neglected Tropical Diseases1935-27271935-27352015-01-0199e000400610.1371/journal.pntd.0004006Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.Leyanna GeorgeAudrey LenhartJoao ToledoAdhara LazaroWai Wai HanRaman VelayudhanSilvia Runge RanzingerOlaf HorstickThe application of the organophosphate larvicide temephos to water storage containers is one of the most commonly employed dengue vector control methods. This systematic literature review is to the knowledge of the authors the first that aims to assess the community-effectiveness of temephos in controlling both vectors and dengue transmission when delivered either as a single intervention or in combination with other interventions. A comprehensive literature search of 6 databases was performed (PubMed, WHOLIS, GIFT, CDSR, EMBASE, Wiley), grey literature and cross references were also screened for relevant studies. Data were extracted and methodological quality of the studies was assessed independently by two reviewers. 27 studies were included in this systematic review (11 single intervention studies and 16 combined intervention studies). All 11 single intervention studies showed consistently that using temephos led to a reduction in entomological indices. Although 11 of the 16 combined intervention studies showed that temephos application together with other chemical vector control methods also reduced entomological indices, this was either not sustained over time or-as in the five remaining studies--failed to reduce the immature stages. The community-effectiveness of temephos was found to be dependent on factors such as quality of delivery, water turnover rate, type of water, and environmental factors such as organic debris, temperature and exposure to sunlight. Timing of temephos deployment and its need for reapplication, along with behavioural factors such as the reluctance of its application to drinking water, and operational aspects such as cost, supplies, time and labour were further limitations identified in this review. In conclusion, when applied as a single intervention, temephos was found to be effective at suppressing entomological indices, however, the same effect has not been observed when temephos was applied in combination with other interventions. There is no evidence to suggest that temephos use is associated with reductions in dengue transmission.https://doi.org/10.1371/journal.pntd.0004006
spellingShingle Leyanna George
Audrey Lenhart
Joao Toledo
Adhara Lazaro
Wai Wai Han
Raman Velayudhan
Silvia Runge Ranzinger
Olaf Horstick
Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.
PLoS Neglected Tropical Diseases
title Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.
title_full Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.
title_fullStr Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.
title_full_unstemmed Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.
title_short Community-Effectiveness of Temephos for Dengue Vector Control: A Systematic Literature Review.
title_sort community effectiveness of temephos for dengue vector control a systematic literature review
url https://doi.org/10.1371/journal.pntd.0004006
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