Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis
While plasmapheresis is well known to significantly improve both retinal findings and systemic manifestations associated with Waldenstrom macroglobulinemia, few reports exist documenting changes in optical coherence tomography angiography (OCT-A). The authors present a case of a patient with Waldens...
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Wiley
2021-01-01
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Series: | Case Reports in Ophthalmological Medicine |
Online Access: | http://dx.doi.org/10.1155/2021/6816195 |
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author | Michael J. Schatz Carl S. Wilkins Oscar Otero-Marquez Toco Y. P. Chui Richard B. Rosen Meenakashi Gupta |
author_facet | Michael J. Schatz Carl S. Wilkins Oscar Otero-Marquez Toco Y. P. Chui Richard B. Rosen Meenakashi Gupta |
author_sort | Michael J. Schatz |
collection | DOAJ |
description | While plasmapheresis is well known to significantly improve both retinal findings and systemic manifestations associated with Waldenstrom macroglobulinemia, few reports exist documenting changes in optical coherence tomography angiography (OCT-A). The authors present a case of a patient with Waldenstrom macroglobulinemia who had resolution of white-centered peripheral retinal lesions and parafoveal outer nuclear layer hyperreflective material following plasmapheresis. Applying image analysis software to before and after OCT-A images, the authors were able to show an objective decrease in retinal capillary and large vessel density following plasmapheresis. This technique can be used to guide treatment and surveillance for patients with hyperviscosity-related retinopathy. |
format | Article |
id | doaj-art-b7a11c0c6ac74fd4ba5b743a034652b1 |
institution | Kabale University |
issn | 2090-6730 |
language | English |
publishDate | 2021-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Ophthalmological Medicine |
spelling | doaj-art-b7a11c0c6ac74fd4ba5b743a034652b12025-02-03T07:24:15ZengWileyCase Reports in Ophthalmological Medicine2090-67302021-01-01202110.1155/2021/6816195Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with PlasmapheresisMichael J. Schatz0Carl S. Wilkins1Oscar Otero-Marquez2Toco Y. P. Chui3Richard B. Rosen4Meenakashi Gupta5The New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryThe New York Eye and Ear InfirmaryWhile plasmapheresis is well known to significantly improve both retinal findings and systemic manifestations associated with Waldenstrom macroglobulinemia, few reports exist documenting changes in optical coherence tomography angiography (OCT-A). The authors present a case of a patient with Waldenstrom macroglobulinemia who had resolution of white-centered peripheral retinal lesions and parafoveal outer nuclear layer hyperreflective material following plasmapheresis. Applying image analysis software to before and after OCT-A images, the authors were able to show an objective decrease in retinal capillary and large vessel density following plasmapheresis. This technique can be used to guide treatment and surveillance for patients with hyperviscosity-related retinopathy.http://dx.doi.org/10.1155/2021/6816195 |
spellingShingle | Michael J. Schatz Carl S. Wilkins Oscar Otero-Marquez Toco Y. P. Chui Richard B. Rosen Meenakashi Gupta Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis Case Reports in Ophthalmological Medicine |
title | Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis |
title_full | Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis |
title_fullStr | Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis |
title_full_unstemmed | Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis |
title_short | Multimodal Imaging of Waldenstrom Macroglobulinemia-Associated Hyperviscosity-Related Retinopathy Treated with Plasmapheresis |
title_sort | multimodal imaging of waldenstrom macroglobulinemia associated hyperviscosity related retinopathy treated with plasmapheresis |
url | http://dx.doi.org/10.1155/2021/6816195 |
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