Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogen

Abstract. Omsk hemorrhagic fever virus (OHFV) is a tick-borne flavivirus associated with acute febrile illness and hemorrhagic disease in humans. OHFV was first identified in 1947 and since its identification has largely remained endemic to the Omsk region of the Russian Federation, where it continu...

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Main Authors: Nidhi P. Kumar, Matthew Hathaway, Matthew K. Demshuk, Taylor O. DeHaven, Stefania M. Farha, Angelena M. Donovan, Andrew J. Burdette, Gracie L. Walls, Kara M. Selesky, Dia C. Beachboard, Christopher C. Stobart, Haijuan Wang
Format: Article
Language:English
Published: Wolters Kluwer Health - Lippincott Williams Wilkins 2025-04-01
Series:​​​​​​​​Infectious Diseases & Immunity
Online Access:http://journals.lww.com/10.1097/ID9.0000000000000156
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author Nidhi P. Kumar
Matthew Hathaway
Matthew K. Demshuk
Taylor O. DeHaven
Stefania M. Farha
Angelena M. Donovan
Andrew J. Burdette
Gracie L. Walls
Kara M. Selesky
Dia C. Beachboard
Christopher C. Stobart
Haijuan Wang
author_facet Nidhi P. Kumar
Matthew Hathaway
Matthew K. Demshuk
Taylor O. DeHaven
Stefania M. Farha
Angelena M. Donovan
Andrew J. Burdette
Gracie L. Walls
Kara M. Selesky
Dia C. Beachboard
Christopher C. Stobart
Haijuan Wang
author_sort Nidhi P. Kumar
collection DOAJ
description Abstract. Omsk hemorrhagic fever virus (OHFV) is a tick-borne flavivirus associated with acute febrile illness and hemorrhagic disease in humans. OHFV was first identified in 1947 and since its identification has largely remained endemic to the Omsk region of the Russian Federation, where it continues to result in illnesses each year. However, the 2 primary tick vectors of OHFV exhibit ranges that extend far beyond the Omsk region, and the recent positive confirmation of OHFV in samples outside of the historic endemic range, in both the Russian Federation and neighboring Kazakhstan, to the south raises new concerns about the future potential of the pathogen. In this review, we comprehensively discuss the emergence, virology, ecology, and disease of OHFV.
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institution OA Journals
issn 2096-9511
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language English
publishDate 2025-04-01
publisher Wolters Kluwer Health - Lippincott Williams Wilkins
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series ​​​​​​​​Infectious Diseases & Immunity
spelling doaj-art-b79fb4584e7041e1a046367209910bd32025-08-20T02:26:58ZengWolters Kluwer Health - Lippincott Williams Wilkins​​​​​​​​Infectious Diseases & Immunity2096-95112693-88392025-04-015213814410.1097/ID9.0000000000000156202504000-00009Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogenNidhi P. Kumar0Matthew Hathaway1Matthew K. Demshuk2Taylor O. DeHaven3Stefania M. Farha4Angelena M. Donovan5Andrew J. Burdette6Gracie L. Walls7Kara M. Selesky8Dia C. Beachboard9Christopher C. Stobart10Haijuan Wang1 Department of Biology, DeSales University, Central Valley, PA 18034, USA2 Department of Medical Microbiology and Immunology, University of Toledo Medical Center, Toledo, OH 43614, USA3 Department of Biological Sciences, Butler University, Indianapolis, IN 46208, USA1 Department of Biology, DeSales University, Central Valley, PA 18034, USA3 Department of Biological Sciences, Butler University, Indianapolis, IN 46208, USA1 Department of Biology, DeSales University, Central Valley, PA 18034, USA3 Department of Biological Sciences, Butler University, Indianapolis, IN 46208, USA3 Department of Biological Sciences, Butler University, Indianapolis, IN 46208, USA1 Department of Biology, DeSales University, Central Valley, PA 18034, USA1 Department of Biology, DeSales University, Central Valley, PA 18034, USA3 Department of Biological Sciences, Butler University, Indianapolis, IN 46208, USAAbstract. Omsk hemorrhagic fever virus (OHFV) is a tick-borne flavivirus associated with acute febrile illness and hemorrhagic disease in humans. OHFV was first identified in 1947 and since its identification has largely remained endemic to the Omsk region of the Russian Federation, where it continues to result in illnesses each year. However, the 2 primary tick vectors of OHFV exhibit ranges that extend far beyond the Omsk region, and the recent positive confirmation of OHFV in samples outside of the historic endemic range, in both the Russian Federation and neighboring Kazakhstan, to the south raises new concerns about the future potential of the pathogen. In this review, we comprehensively discuss the emergence, virology, ecology, and disease of OHFV.http://journals.lww.com/10.1097/ID9.0000000000000156
spellingShingle Nidhi P. Kumar
Matthew Hathaway
Matthew K. Demshuk
Taylor O. DeHaven
Stefania M. Farha
Angelena M. Donovan
Andrew J. Burdette
Gracie L. Walls
Kara M. Selesky
Dia C. Beachboard
Christopher C. Stobart
Haijuan Wang
Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogen
​​​​​​​​Infectious Diseases & Immunity
title Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogen
title_full Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogen
title_fullStr Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogen
title_full_unstemmed Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogen
title_short Omsk hemorrhagic fever virus: review of the biology, ecology, and disease associated with a historic tick-borne pathogen
title_sort omsk hemorrhagic fever virus review of the biology ecology and disease associated with a historic tick borne pathogen
url http://journals.lww.com/10.1097/ID9.0000000000000156
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