Hydrogen sulfide (H2S) coordinates redox balance, carbon metabolism, and mitochondrial bioenergetics to suppress SARS-CoV-2 infection.

Hydrogen sulfide (H2S) coordinates redox balance, carbon metabolism, and mitochondrial bioenergetics to suppress SARS-CoV-2 infection.

Viruses modulate various aspects of host physiology, including carbon metabolism, redox balance, and mitochondrial bioenergetics to acquire the building blocks for replication and regulation of the immune response. Understanding how SARS-CoV-2 alters the host metabolism may lead to treatments for CO...

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Main Authors: Ragini Agrawal, Virender Kumar Pal, Suhas K S, Gopika Jayan Menon, Inder Raj Singh, Nitish Malhotra, Naren C S, Kailash Ganesh, Raju S Rajmani, Aswin Sai Narain Seshasayee, Nagasuma Chandra, Manjunath B Joshi, Amit Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013164
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