Treatment of calcium pyrophosphate crystal deposition disease: a mini-review
Calcium pyrophosphate crystal deposition disease is a prevalent and impactful form of crystal arthropathy. It usually targets the large joints of the extremities, significantly affecting daily life. Progression of this disease, commonly observed in older individuals and often mistaken for septic art...
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| Format: | Article |
| Language: | English |
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Open Exploration Publishing Inc.
2025-08-01
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| Series: | Exploration of Musculoskeletal Diseases |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A1007100/1007100.pdf |
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| author | Ebru Atalar Hatice Bodur |
| author_facet | Ebru Atalar Hatice Bodur |
| author_sort | Ebru Atalar |
| collection | DOAJ |
| description | Calcium pyrophosphate crystal deposition disease is a prevalent and impactful form of crystal arthropathy. It usually targets the large joints of the extremities, significantly affecting daily life. Progression of this disease, commonly observed in older individuals and often mistaken for septic arthritis, osteoarthritis, or several rheumatic conditions, remains poorly understood. The disease can present in various forms, from asymptomatic to severe joint deformity. The primary goal of treating this disease is to firmly control inflammation, prevent joint deformities, and decisively stop attacks. Medications used to treat the disease include anti-rheumatic drugs such as non-steroidal anti-inflammatory drugs, oral, intramuscular, or intra-articular steroids, hydroxychloroquine, colchicine, methotrexate, and interleukin-1 receptor antagonists. Radiosynovectomy is a radioactive technique that effectively targets and eliminates inflamed synovium. This article highlights the importance of awareness and early intervention to manage this condition effectively. |
| format | Article |
| id | doaj-art-b77d46c53d7b4e308b03faeec79a912f |
| institution | Kabale University |
| issn | 2836-6468 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Musculoskeletal Diseases |
| spelling | doaj-art-b77d46c53d7b4e308b03faeec79a912f2025-08-22T08:08:16ZengOpen Exploration Publishing Inc.Exploration of Musculoskeletal Diseases2836-64682025-08-013100710010.37349/emd.2025.1007100Treatment of calcium pyrophosphate crystal deposition disease: a mini-reviewEbru Atalar0https://orcid.org/0000-0003-2708-0373Hatice Bodur1https://orcid.org/0000-0003-3008-7007Department of Rheumatology, Ankara Bilkent City Hospital, Ankara 06800, TurkeyDepartment of Physical Medicine and Rehabilitation, Faculty of Medicine, Ankara Yildirim Beyazit University, Ankara 06800, TurkeyCalcium pyrophosphate crystal deposition disease is a prevalent and impactful form of crystal arthropathy. It usually targets the large joints of the extremities, significantly affecting daily life. Progression of this disease, commonly observed in older individuals and often mistaken for septic arthritis, osteoarthritis, or several rheumatic conditions, remains poorly understood. The disease can present in various forms, from asymptomatic to severe joint deformity. The primary goal of treating this disease is to firmly control inflammation, prevent joint deformities, and decisively stop attacks. Medications used to treat the disease include anti-rheumatic drugs such as non-steroidal anti-inflammatory drugs, oral, intramuscular, or intra-articular steroids, hydroxychloroquine, colchicine, methotrexate, and interleukin-1 receptor antagonists. Radiosynovectomy is a radioactive technique that effectively targets and eliminates inflamed synovium. This article highlights the importance of awareness and early intervention to manage this condition effectively.https://www.explorationpub.com/uploads/Article/A1007100/1007100.pdfcalcium pyrophosphate crystal deposition diseaseacute arthritiscrystalsosteoarthritistreatment |
| spellingShingle | Ebru Atalar Hatice Bodur Treatment of calcium pyrophosphate crystal deposition disease: a mini-review Exploration of Musculoskeletal Diseases calcium pyrophosphate crystal deposition disease acute arthritis crystals osteoarthritis treatment |
| title | Treatment of calcium pyrophosphate crystal deposition disease: a mini-review |
| title_full | Treatment of calcium pyrophosphate crystal deposition disease: a mini-review |
| title_fullStr | Treatment of calcium pyrophosphate crystal deposition disease: a mini-review |
| title_full_unstemmed | Treatment of calcium pyrophosphate crystal deposition disease: a mini-review |
| title_short | Treatment of calcium pyrophosphate crystal deposition disease: a mini-review |
| title_sort | treatment of calcium pyrophosphate crystal deposition disease a mini review |
| topic | calcium pyrophosphate crystal deposition disease acute arthritis crystals osteoarthritis treatment |
| url | https://www.explorationpub.com/uploads/Article/A1007100/1007100.pdf |
| work_keys_str_mv | AT ebruatalar treatmentofcalciumpyrophosphatecrystaldepositiondiseaseaminireview AT haticebodur treatmentofcalciumpyrophosphatecrystaldepositiondiseaseaminireview |