Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension
Abstract Background Heart failure with preserved ejection fraction (HFpEF) poses a significant clinical challenge, especially in older patients with HT. This study aimed to identify the factors influencing HFpEF occurrence in elderly patients with HT. Methods Elderly patients with HT were categorize...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | BMC Cardiovascular Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12872-024-04419-4 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850034980304977920 |
|---|---|
| author | Min Chen Wentao Li Qin Ran |
| author_facet | Min Chen Wentao Li Qin Ran |
| author_sort | Min Chen |
| collection | DOAJ |
| description | Abstract Background Heart failure with preserved ejection fraction (HFpEF) poses a significant clinical challenge, especially in older patients with HT. This study aimed to identify the factors influencing HFpEF occurrence in elderly patients with HT. Methods Elderly patients with HT were categorized into two groups: no HFpEF group and HFpEF group based on HFpEF diagnosis. Demographic, clinical, laboratory and echocardiographic data was conducted. Logistic regression analysis and joint prediction modeling were used to identify predictive factors for HFpEF. Results Several factors were associated with HFpEF, including age, body mass index, duration of HT, atrial fibrillation (AF), chronic kidney disease (CKD), stroke, systolic blood pressure (SBP), serum creatinine (SCr), N-terminal pro brain natriuretic peptide (NT-proBNP), heart rate, serum sodium, low density lipoprotein cholesterol (LDL-c), triglyceride, left ventricular ejection fraction (LVEF), E/e’ ratio, left atrial diameter, tricuspid regurgitation velocity, mitral regurgitation and C-reactive protein (CRP) levels. The joint prediction model shown high accuracy, with an area under the curve (AUC) of 0.840. Conclusions This study provided insights into the incidence rate and risk factors of HFpEF in elderly patients with HT. Key determinants included age, blood pressure, biomarkers, and echocardiographic parameters. |
| format | Article |
| id | doaj-art-b7775f6d308c43fdaea0be9b7971e8f7 |
| institution | DOAJ |
| issn | 1471-2261 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj-art-b7775f6d308c43fdaea0be9b7971e8f72025-08-20T02:57:39ZengBMCBMC Cardiovascular Disorders1471-22612024-12-012411810.1186/s12872-024-04419-4Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertensionMin Chen0Wentao Li1Qin Ran2Department of cardiovascular medicine, Chengdu Seventh People’s HospitalDepartment of Internal Medicine, West China Second Hospital, Sichuan UniversityDepartment of cardiovascular medicine, Chengdu Seventh People’s HospitalAbstract Background Heart failure with preserved ejection fraction (HFpEF) poses a significant clinical challenge, especially in older patients with HT. This study aimed to identify the factors influencing HFpEF occurrence in elderly patients with HT. Methods Elderly patients with HT were categorized into two groups: no HFpEF group and HFpEF group based on HFpEF diagnosis. Demographic, clinical, laboratory and echocardiographic data was conducted. Logistic regression analysis and joint prediction modeling were used to identify predictive factors for HFpEF. Results Several factors were associated with HFpEF, including age, body mass index, duration of HT, atrial fibrillation (AF), chronic kidney disease (CKD), stroke, systolic blood pressure (SBP), serum creatinine (SCr), N-terminal pro brain natriuretic peptide (NT-proBNP), heart rate, serum sodium, low density lipoprotein cholesterol (LDL-c), triglyceride, left ventricular ejection fraction (LVEF), E/e’ ratio, left atrial diameter, tricuspid regurgitation velocity, mitral regurgitation and C-reactive protein (CRP) levels. The joint prediction model shown high accuracy, with an area under the curve (AUC) of 0.840. Conclusions This study provided insights into the incidence rate and risk factors of HFpEF in elderly patients with HT. Key determinants included age, blood pressure, biomarkers, and echocardiographic parameters.https://doi.org/10.1186/s12872-024-04419-4Incidence rateRisk factorsHFpEFElderlyHypertension |
| spellingShingle | Min Chen Wentao Li Qin Ran Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension BMC Cardiovascular Disorders Incidence rate Risk factors HFpEF Elderly Hypertension |
| title | Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension |
| title_full | Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension |
| title_fullStr | Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension |
| title_full_unstemmed | Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension |
| title_short | Incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension |
| title_sort | incidence and risk factors of heart failure with preserved ejection fraction in elderly patients with hypertension |
| topic | Incidence rate Risk factors HFpEF Elderly Hypertension |
| url | https://doi.org/10.1186/s12872-024-04419-4 |
| work_keys_str_mv | AT minchen incidenceandriskfactorsofheartfailurewithpreservedejectionfractioninelderlypatientswithhypertension AT wentaoli incidenceandriskfactorsofheartfailurewithpreservedejectionfractioninelderlypatientswithhypertension AT qinran incidenceandriskfactorsofheartfailurewithpreservedejectionfractioninelderlypatientswithhypertension |