DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER
Antiphospholipid syndrome (APS) is an immune-mediated violation of coagulation, the diagnosis of which requires mandatory laboratory confirmation. Since the clinical manifestations of APS are extremely diverse, various specialists are involved in the diagnostic process – neurology, cardiologists, su...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«REMEDIUM GROUP» Ltd.
2019-06-01
|
| Series: | Атеротромбоз |
| Subjects: | |
| Online Access: | https://www.aterotromboz.ru/jour/article/view/187 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849763081338486784 |
|---|---|
| author | T. V. Vavilova L. A. Isaeva K. Yu. Grinchenko Ju. D. Bogatenkova V. A. Sorokoumov |
| author_facet | T. V. Vavilova L. A. Isaeva K. Yu. Grinchenko Ju. D. Bogatenkova V. A. Sorokoumov |
| author_sort | T. V. Vavilova |
| collection | DOAJ |
| description | Antiphospholipid syndrome (APS) is an immune-mediated violation of coagulation, the diagnosis of which requires mandatory laboratory confirmation. Since the clinical manifestations of APS are extremely diverse, various specialists are involved in the diagnostic process – neurology, cardiologists, surgeons, hematologists, endocrinologists, laboratory medicine specialists, etc. So far, it remains an open question what specialist exactly should make the final diagnosis and supervise patient with APS. The experience of a separate diagnostic center shows the distribution of prescriptions and their compliance with the international recommendations. This study also provides data on the frequency of prescribing laboratory tests to confirm APS, which is 1.2% of all coagulation tests. Among the patients with suspected APS on the basis of clinical signs, only 12.2% of the diagnosis was confirmed. Presents the dangers of obtaining false-positive results that should be taken into account when prescribing laboratory tests. |
| format | Article |
| id | doaj-art-b775f409f7db42ce89456dac31ce0c07 |
| institution | DOAJ |
| issn | 2307-1109 2658-5952 |
| language | Russian |
| publishDate | 2019-06-01 |
| publisher | «REMEDIUM GROUP» Ltd. |
| record_format | Article |
| series | Атеротромбоз |
| spelling | doaj-art-b775f409f7db42ce89456dac31ce0c072025-08-20T03:05:31Zrus«REMEDIUM GROUP» Ltd.Атеротромбоз2307-11092658-59522019-06-0101929810.21518/2307-1109-2019-1-92-98165DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTERT. V. Vavilova0L. A. Isaeva1K. Yu. Grinchenko2Ju. D. Bogatenkova3V. A. Sorokoumov4Federal State Budgetary Institution “Almazov National Medical Research Center” of the Ministry of Health Saint-Petersburg State Budgetary Health Institution “City Consulting and Diagnostic Center № 1”Saint-Petersburg State Budgetary Health Institution “City Consulting and Diagnostic Center № 1”Federal State Budgetary Institution “Almazov National Medical Research Center” of the Ministry of HealthSaint-Petersburg State Budgetary Health Institution “City Consulting and Diagnostic Center № 1”Saint-Petersburg State Budgetary Health Institution “City Consulting and Diagnostic Center № 1” Federal State Budgetary Educational Institution of Higher Education “Academician I.P. Pavlov First St. Petersburg State Medical University” of the Ministry of HealthcareAntiphospholipid syndrome (APS) is an immune-mediated violation of coagulation, the diagnosis of which requires mandatory laboratory confirmation. Since the clinical manifestations of APS are extremely diverse, various specialists are involved in the diagnostic process – neurology, cardiologists, surgeons, hematologists, endocrinologists, laboratory medicine specialists, etc. So far, it remains an open question what specialist exactly should make the final diagnosis and supervise patient with APS. The experience of a separate diagnostic center shows the distribution of prescriptions and their compliance with the international recommendations. This study also provides data on the frequency of prescribing laboratory tests to confirm APS, which is 1.2% of all coagulation tests. Among the patients with suspected APS on the basis of clinical signs, only 12.2% of the diagnosis was confirmed. Presents the dangers of obtaining false-positive results that should be taken into account when prescribing laboratory tests.https://www.aterotromboz.ru/jour/article/view/187antiphospholipid syndromelaboratory testsdiagnostic criteria |
| spellingShingle | T. V. Vavilova L. A. Isaeva K. Yu. Grinchenko Ju. D. Bogatenkova V. A. Sorokoumov DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER Атеротромбоз antiphospholipid syndrome laboratory tests diagnostic criteria |
| title | DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER |
| title_full | DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER |
| title_fullStr | DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER |
| title_full_unstemmed | DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER |
| title_short | DIAGNOSIS OF ANTIPHOSPHOLIPID SYNDROME IN PEOPLE WITH CLINICAL CRITERIA OF THE DISEASE. EXPERIENCE OF A SEPARATE OUTPATIENT CENTER |
| title_sort | diagnosis of antiphospholipid syndrome in people with clinical criteria of the disease experience of a separate outpatient center |
| topic | antiphospholipid syndrome laboratory tests diagnostic criteria |
| url | https://www.aterotromboz.ru/jour/article/view/187 |
| work_keys_str_mv | AT tvvavilova diagnosisofantiphospholipidsyndromeinpeoplewithclinicalcriteriaofthediseaseexperienceofaseparateoutpatientcenter AT laisaeva diagnosisofantiphospholipidsyndromeinpeoplewithclinicalcriteriaofthediseaseexperienceofaseparateoutpatientcenter AT kyugrinchenko diagnosisofantiphospholipidsyndromeinpeoplewithclinicalcriteriaofthediseaseexperienceofaseparateoutpatientcenter AT judbogatenkova diagnosisofantiphospholipidsyndromeinpeoplewithclinicalcriteriaofthediseaseexperienceofaseparateoutpatientcenter AT vasorokoumov diagnosisofantiphospholipidsyndromeinpeoplewithclinicalcriteriaofthediseaseexperienceofaseparateoutpatientcenter |