Analysis of disease severity and mortality prediction using machine learning during COVID-19

This paper focuses on how machine learning (ML) algorithms and applications have been used to analyze disease severity and mortality prediction in COVID-19 research. In the past, simpler statistical and epidemiological methods were more commonly used by researchers and officials to predict the cours...

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Main Authors: Hodjat (Hojatollah) Hamidi, Mostafa Moradi
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Acta Psychologica
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Online Access:http://www.sciencedirect.com/science/article/pii/S0001691825004494
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author Hodjat (Hojatollah) Hamidi
Mostafa Moradi
author_facet Hodjat (Hojatollah) Hamidi
Mostafa Moradi
author_sort Hodjat (Hojatollah) Hamidi
collection DOAJ
description This paper focuses on how machine learning (ML) algorithms and applications have been used to analyze disease severity and mortality prediction in COVID-19 research. In the past, simpler statistical and epidemiological methods were more commonly used by researchers and officials to predict the course of the pandemic. However, in recent years, the limitations, high costs, and time required for medical tests have become significant challenges in stopping the spread of COVID-19. Some improved statistical methods have been used to tackle these challenges, but they have only partially solved the problems at a certain quality level. On the other hand, machine learning offers a wide range of smart methods, frameworks, and tools to deal with problems in the medical field. In this paper, using public and clinical data from patients, the severity and risk of death are studied through different machine learning algorithms, and the most important features in this area are identified. The main innovation of this paper is the comparative analysis of different models for diagnosis using statistical data. First, the COVID-19 dataset is preprocessed, and then several well-known models in disease classification are used, and their accuracy is compared. This study helps healthcare centers and hospitals prioritize the allocation of medical resources based on the severity of patients' conditions and predict their chances of survival. With data from over one million patients and the evaluation of >12 models, the Logistic Regression model generally shows the highest accuracy for both class 0 and class 1. In various situations, this model achieved the highest accuracy for class 0 (97 %) and for class 1 (80 %). Therefore, it can be concluded that the Logistic Regression model performs best in diagnosing both classes.
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spelling doaj-art-b76da122d2f74e96b959f455349527d42025-08-20T03:31:11ZengElsevierActa Psychologica0001-69182025-08-0125810513610.1016/j.actpsy.2025.105136Analysis of disease severity and mortality prediction using machine learning during COVID-19Hodjat (Hojatollah) Hamidi0Mostafa Moradi1Corresponding author at: K. N. Toosi University of Technology, Department of Industrial Engineering, Information Technology Group, Mollasadra St, Tehran, Iran.; Department of Industrial Engineering, Information Technology Group, K. N. Toosi University of Technology, Tehran, IranDepartment of Industrial Engineering, Information Technology Group, K. N. Toosi University of Technology, Tehran, IranThis paper focuses on how machine learning (ML) algorithms and applications have been used to analyze disease severity and mortality prediction in COVID-19 research. In the past, simpler statistical and epidemiological methods were more commonly used by researchers and officials to predict the course of the pandemic. However, in recent years, the limitations, high costs, and time required for medical tests have become significant challenges in stopping the spread of COVID-19. Some improved statistical methods have been used to tackle these challenges, but they have only partially solved the problems at a certain quality level. On the other hand, machine learning offers a wide range of smart methods, frameworks, and tools to deal with problems in the medical field. In this paper, using public and clinical data from patients, the severity and risk of death are studied through different machine learning algorithms, and the most important features in this area are identified. The main innovation of this paper is the comparative analysis of different models for diagnosis using statistical data. First, the COVID-19 dataset is preprocessed, and then several well-known models in disease classification are used, and their accuracy is compared. This study helps healthcare centers and hospitals prioritize the allocation of medical resources based on the severity of patients' conditions and predict their chances of survival. With data from over one million patients and the evaluation of >12 models, the Logistic Regression model generally shows the highest accuracy for both class 0 and class 1. In various situations, this model achieved the highest accuracy for class 0 (97 %) and for class 1 (80 %). Therefore, it can be concluded that the Logistic Regression model performs best in diagnosing both classes.http://www.sciencedirect.com/science/article/pii/S0001691825004494Covid-19Disease diagnosisMachine learningMortality predictionHealthcare resource allocation
spellingShingle Hodjat (Hojatollah) Hamidi
Mostafa Moradi
Analysis of disease severity and mortality prediction using machine learning during COVID-19
Acta Psychologica
Covid-19
Disease diagnosis
Machine learning
Mortality prediction
Healthcare resource allocation
title Analysis of disease severity and mortality prediction using machine learning during COVID-19
title_full Analysis of disease severity and mortality prediction using machine learning during COVID-19
title_fullStr Analysis of disease severity and mortality prediction using machine learning during COVID-19
title_full_unstemmed Analysis of disease severity and mortality prediction using machine learning during COVID-19
title_short Analysis of disease severity and mortality prediction using machine learning during COVID-19
title_sort analysis of disease severity and mortality prediction using machine learning during covid 19
topic Covid-19
Disease diagnosis
Machine learning
Mortality prediction
Healthcare resource allocation
url http://www.sciencedirect.com/science/article/pii/S0001691825004494
work_keys_str_mv AT hodjathojatollahhamidi analysisofdiseaseseverityandmortalitypredictionusingmachinelearningduringcovid19
AT mostafamoradi analysisofdiseaseseverityandmortalitypredictionusingmachinelearningduringcovid19