Nanomedicine Penetrating Blood‐Pancreas Barrier for Effective Treatment of Acute Pancreatitis

Nanomedicine Penetrating Blood‐Pancreas Barrier for Effective Treatment of Acute Pancreatitis

Abstract Acute pancreatitis (AP) is a primary contributor to hospitalization and in‐hospital mortality worldwide. Targeted elimination of mitochondrial reactive oxygen species (mtROS) within pancreatic acinar cells (PACs) represents an ideal strategy for treating AP. However, existing drugs fail to...

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Bibliographic Details
Main Authors: Dan Wang, Shuya Wang, Jinjin Liu, Xiaojing Shi, Tingli Xiong, Ruishi Li, Wei Wei, Liandong Ji, Qiong Huang, Xuejun Gong, Kelong Ai
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
acute pancreatitis
blood‐pancreas barriers
cGAS, mitochondrial targeting
reactive oxygen species
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Online Access:https://doi.org/10.1002/advs.202413925
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