Sirt6 ameliorates high glucose-induced podocyte cytoskeleton remodeling via the PI3K/AKT signaling pathway

Sirt6 ameliorates high glucose-induced podocyte cytoskeleton remodeling via the PI3K/AKT signaling pathway

Background Podocyte injury plays an important role in the occurrence and progression of diabetic kidney disease (DKD), which leads to albuminuria. Cytoskeletal remodeling is an early manifestation of podocyte injury in DKD. However, the underlying mechanism of cytoskeletal remodeling has not been cl...

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Bibliographic Details
Main Authors: Zongwei Zhang, Hao Huang, Yu Tao, Hongyan Liu, Yanqin Fan
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Renal Failure
Subjects:
Sirt6
diabetic kidney disease
podocyte injury
cytoskeletal remodeling
PI3K/AKT signaling pathway
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2410396
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