Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients

Purpose: to determine whether there is any difference in autonomic innervation of the cardio-vascular system in normal tension glaucoma (NtG) patients and primary open angle glaucoma (POAG) patients.Methods: 30 NtG patients, 30 POAG patients and 22 control group patients underwent photoplethysmograp...

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Main Authors: N. I. Kurysheva, V. N. Trubilin, M. A. Tsaregorodtseva, T. Ya. Ryabova, V. N. Shlapak, E. Yu. Irtegova
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2014-07-01
Series:Oftalʹmologiâ
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Online Access:https://www.ophthalmojournal.com/opht/article/view/76
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author N. I. Kurysheva
V. N. Trubilin
M. A. Tsaregorodtseva
T. Ya. Ryabova
V. N. Shlapak
E. Yu. Irtegova
author_facet N. I. Kurysheva
V. N. Trubilin
M. A. Tsaregorodtseva
T. Ya. Ryabova
V. N. Shlapak
E. Yu. Irtegova
author_sort N. I. Kurysheva
collection DOAJ
description Purpose: to determine whether there is any difference in autonomic innervation of the cardio-vascular system in normal tension glaucoma (NtG) patients and primary open angle glaucoma (POAG) patients.Methods: 30 NtG patients, 30 POAG patients and 22 control group patients underwent photoplethysmography following cold provocation testing. Several parameters showing cardio-vascular innervation have been evaluated and compared in three groups.Results: the three selected parameters demonstrated the dominance of the sympathetic nervous system over parasympathetic nervous system in both glaucoma groups (NtG and POAG) and not in the control group. In contrast to POAG and the control group, the NtG patients showed strong increase in sympathetic nervous system activity following the cold provocation test.Conclusion: Our studies revealed the dominance of sympathetic innervation in glaucoma patients in general. the cold provocationtest results strongly suggest primary vascular dysregulation in NtG patients.
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spelling doaj-art-b75df46abe944662aac5a8fdbc3632c62025-08-20T03:22:12ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-0191444810.18008/1816-5095-2012-1-44-4876Autonomic innervation of the cardio-vascular system in normal tension glaucoma patientsN. I. Kurysheva0V. N. Trubilin1M. A. Tsaregorodtseva2T. Ya. Ryabova3V. N. Shlapak4E. Yu. Irtegova5Центр офтальмологии ФМБА России, МоскваЦентр офтальмологии ФМБА России, МоскваЦентр офтальмологии ФМБА России, МоскваФГУП Научно-технический центр радиационно-химической безопасности и гигиены ФМБА России, МоскваФГУП Научно-технический центр радиационно-химической безопасности и гигиены ФМБА России, МоскваЦентр офтальмологии ФМБА России, Москва, РоссияPurpose: to determine whether there is any difference in autonomic innervation of the cardio-vascular system in normal tension glaucoma (NtG) patients and primary open angle glaucoma (POAG) patients.Methods: 30 NtG patients, 30 POAG patients and 22 control group patients underwent photoplethysmography following cold provocation testing. Several parameters showing cardio-vascular innervation have been evaluated and compared in three groups.Results: the three selected parameters demonstrated the dominance of the sympathetic nervous system over parasympathetic nervous system in both glaucoma groups (NtG and POAG) and not in the control group. In contrast to POAG and the control group, the NtG patients showed strong increase in sympathetic nervous system activity following the cold provocation test.Conclusion: Our studies revealed the dominance of sympathetic innervation in glaucoma patients in general. the cold provocationtest results strongly suggest primary vascular dysregulation in NtG patients.https://www.ophthalmojournal.com/opht/article/view/76normal tension glaucomavascular dysregulationcold provocationautonomic nervous system
spellingShingle N. I. Kurysheva
V. N. Trubilin
M. A. Tsaregorodtseva
T. Ya. Ryabova
V. N. Shlapak
E. Yu. Irtegova
Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients
Oftalʹmologiâ
normal tension glaucoma
vascular dysregulation
cold provocation
autonomic nervous system
title Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients
title_full Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients
title_fullStr Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients
title_full_unstemmed Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients
title_short Autonomic innervation of the cardio-vascular system in normal tension glaucoma patients
title_sort autonomic innervation of the cardio vascular system in normal tension glaucoma patients
topic normal tension glaucoma
vascular dysregulation
cold provocation
autonomic nervous system
url https://www.ophthalmojournal.com/opht/article/view/76
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AT vntrubilin autonomicinnervationofthecardiovascularsysteminnormaltensionglaucomapatients
AT matsaregorodtseva autonomicinnervationofthecardiovascularsysteminnormaltensionglaucomapatients
AT tyaryabova autonomicinnervationofthecardiovascularsysteminnormaltensionglaucomapatients
AT vnshlapak autonomicinnervationofthecardiovascularsysteminnormaltensionglaucomapatients
AT eyuirtegova autonomicinnervationofthecardiovascularsysteminnormaltensionglaucomapatients