Tc-99m-PSMA-SPECT/CT Is Superior to Tc-99m-MDP-SPECT/CT in the Staging of Prostatic Cancer with Osseous Metastases after External Beam Radiotherapy

In the reported patient with advanced prostate cancer, a bone scan showed a false positive finding in thoracic vertebrae bone metastasis after external beam radiotherapy 2 months ago. An additional Tc-99m-prostate-specific membrane antigen scan showed a negative finding, although nonirradiated iliac...

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Bibliographic Details
Main Authors: Knut Liepe, Marcel Baehr
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-03-01
Series:World Journal of Nuclear Medicine
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1744200
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Summary:In the reported patient with advanced prostate cancer, a bone scan showed a false positive finding in thoracic vertebrae bone metastasis after external beam radiotherapy 2 months ago. An additional Tc-99m-prostate-specific membrane antigen scan showed a negative finding, although nonirradiated iliac bone metastasis was concordantly positive in both scans. The decrease in prostate-specific antigen-level from 156.6 ng/mL to 2.3 ng/mL indicates a strong effect of treatment, hence supporting false positivity in bone scan by flare phenomenon.
ISSN:1450-1147
1607-3312