Mechanism of Ershen Zhenwu Decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation

Mechanism of Ershen Zhenwu Decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation

BackgroundChronic heart failure (CHF) is a complex cardiovascular disease caused by different pathological mechanisms. Modern medicine has made advancements in CHF treatment; however, there are still many challenges. Ershen Zhenwu Decoction (ESZWD) is a Xin'an medicine that has been clinically...

Full description

Saved in:
Bibliographic Details
Main Authors: Yulong Liu, Xinyue Wang, Maomao Zhang, Dan Cheng, Zhenpeng Zhu, Lan Ge, Xiaoyu Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Ershen Zhenwu decoction
network pharmacology
molecular docking
JNK/MAPK
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1561963/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items