Noncontact Meibography in Patients with Keratoconus
Purpose. To examine the morphological changes in the meibomian glands of patients with keratoconus as well as to study the relationship between these changes in the morphology and several tear film parameters. Methods. Examination of the meibomian gland (MG) of 300 keratoconus patients presenting to...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2019/2965872 |
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| author | Engy Mohamed Mostafa Marwa Mahmoud Abdellah Ashraf Mostafa Elhawary Amr Mounir |
| author_facet | Engy Mohamed Mostafa Marwa Mahmoud Abdellah Ashraf Mostafa Elhawary Amr Mounir |
| author_sort | Engy Mohamed Mostafa |
| collection | DOAJ |
| description | Purpose. To examine the morphological changes in the meibomian glands of patients with keratoconus as well as to study the relationship between these changes in the morphology and several tear film parameters. Methods. Examination of the meibomian gland (MG) of 300 keratoconus patients presenting to the center using infrared noncontact meibography system (Sirius, CSO, Italy) between January 2017—January 2019. 100 eyes of healthy individuals were also enrolled as a control group. Tear breakup time (TBUT) test and Schirmer test II were evaluated. Subjective symptoms were also assessed using Ocular Surface Disease Index (OSDI). Results. Mean age of keratoconus patients was 19 ± 12 years and 21 ± 14 years in control group. Average TBUT was 4.9 ± 2.1 sec. and average Schirmer test was 5.3 ± 2.2 mm which was significantly lower than control group (p=0.05). Meibomian gland dropout in the lower eyelid of the keratoconus group was as follows: grade 0 (no loss of meibomian glands): 100 eyes; grade 1 (gland dropout area <1/3 of the total meibomian glands): 85 eyes; grade 2 (gland dropout area 1/3 to 2/3): 68 eyes; and grade 3 (gland dropout >2/3): 47 eyes. Conclusion. Keratoconus shows significant meibomian gland dropout and distortion that can be recorded by noncontact meibography. Sirius meibography is a simple, cost-effective method of evaluating meibomian gland dropout as a part of the routine refractive examination. |
| format | Article |
| id | doaj-art-b748c9840fd34bd8a5dbda0d52a0e72a |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-b748c9840fd34bd8a5dbda0d52a0e72a2025-08-20T03:39:29ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/29658722965872Noncontact Meibography in Patients with KeratoconusEngy Mohamed Mostafa0Marwa Mahmoud Abdellah1Ashraf Mostafa Elhawary2Amr Mounir3Ophthalmology Department, Faculty of Medicine, Sohag University, Sohag, EgyptOphthalmology Department, Faculty of Medicine, Sohag University, Sohag, EgyptOphthalmology Department, Faculty of Medicine, Sohag University, Sohag, EgyptOphthalmology Department, Faculty of Medicine, Sohag University, Sohag, EgyptPurpose. To examine the morphological changes in the meibomian glands of patients with keratoconus as well as to study the relationship between these changes in the morphology and several tear film parameters. Methods. Examination of the meibomian gland (MG) of 300 keratoconus patients presenting to the center using infrared noncontact meibography system (Sirius, CSO, Italy) between January 2017—January 2019. 100 eyes of healthy individuals were also enrolled as a control group. Tear breakup time (TBUT) test and Schirmer test II were evaluated. Subjective symptoms were also assessed using Ocular Surface Disease Index (OSDI). Results. Mean age of keratoconus patients was 19 ± 12 years and 21 ± 14 years in control group. Average TBUT was 4.9 ± 2.1 sec. and average Schirmer test was 5.3 ± 2.2 mm which was significantly lower than control group (p=0.05). Meibomian gland dropout in the lower eyelid of the keratoconus group was as follows: grade 0 (no loss of meibomian glands): 100 eyes; grade 1 (gland dropout area <1/3 of the total meibomian glands): 85 eyes; grade 2 (gland dropout area 1/3 to 2/3): 68 eyes; and grade 3 (gland dropout >2/3): 47 eyes. Conclusion. Keratoconus shows significant meibomian gland dropout and distortion that can be recorded by noncontact meibography. Sirius meibography is a simple, cost-effective method of evaluating meibomian gland dropout as a part of the routine refractive examination.http://dx.doi.org/10.1155/2019/2965872 |
| spellingShingle | Engy Mohamed Mostafa Marwa Mahmoud Abdellah Ashraf Mostafa Elhawary Amr Mounir Noncontact Meibography in Patients with Keratoconus Journal of Ophthalmology |
| title | Noncontact Meibography in Patients with Keratoconus |
| title_full | Noncontact Meibography in Patients with Keratoconus |
| title_fullStr | Noncontact Meibography in Patients with Keratoconus |
| title_full_unstemmed | Noncontact Meibography in Patients with Keratoconus |
| title_short | Noncontact Meibography in Patients with Keratoconus |
| title_sort | noncontact meibography in patients with keratoconus |
| url | http://dx.doi.org/10.1155/2019/2965872 |
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