Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology

Microalgae are emerging as a key player in healthcare, functional foods, and sustainable biotech due to their capacity to produce bioactive compounds like β-glucans, omega-3 fatty acids, and antioxidants in an eco-friendly manner. This review comprehensively discusses the role of microalgae in healt...

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Main Authors: Chao Li, Ming Du, Yujie Han, Wentao Sun, Zixi Chen, Qiong Liu, Hui Zhu, Liqing Zhao, Shuangfei Li, Jiangxin Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1557298/full
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author Chao Li
Chao Li
Chao Li
Ming Du
Yujie Han
Wentao Sun
Zixi Chen
Qiong Liu
Hui Zhu
Liqing Zhao
Shuangfei Li
Jiangxin Wang
author_facet Chao Li
Chao Li
Chao Li
Ming Du
Yujie Han
Wentao Sun
Zixi Chen
Qiong Liu
Hui Zhu
Liqing Zhao
Shuangfei Li
Jiangxin Wang
author_sort Chao Li
collection DOAJ
description Microalgae are emerging as a key player in healthcare, functional foods, and sustainable biotech due to their capacity to produce bioactive compounds like β-glucans, omega-3 fatty acids, and antioxidants in an eco-friendly manner. This review comprehensively discusses the role of microalgae in healthcare and functional foods, focusing particularly on β-glucan therapeutics, drug delivery innovations, and synthetic biology applications. In healthcare, microalgae-derived compounds show immense promise for treating diseases, boosting immunity, and tackling oxidative stress. Euglena-derived paramylon, a type of β-glucan, has shown potential in various medical applications, including immunomodulation and anticancer therapy. Synthetic biology and bioprocess engineering are enhancing microalgae’s therapeutic and nutritional value, with applications in drug delivery and personalized medicine. To maximize the potential of microalgae, further research and development are needed to address scalability, regulatory alignment, and consumer acceptance, with a focus on interdisciplinary collaboration and sustainable practices to align healthcare innovation with environmental conservation.
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institution OA Journals
issn 1663-9812
language English
publishDate 2025-03-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Pharmacology
spelling doaj-art-b744fa1546c8426fae435386f81bbdd12025-08-20T02:02:52ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-03-011610.3389/fphar.2025.15572981557298Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biologyChao Li0Chao Li1Chao Li2Ming Du3Yujie Han4Wentao Sun5Zixi Chen6Qiong Liu7Hui Zhu8Liqing Zhao9Shuangfei Li10Jiangxin Wang11College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, ChinaSchool of Life Sciences and Food Engineering, Hanshan Normal University, Chaozhou, Guangdong, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaSchool of Life Sciences and Food Engineering, Hanshan Normal University, Chaozhou, Guangdong, ChinaCollege of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaShenzhen Key Laboratory of Marine Bioresource and Eco-environmental Science, Shenzhen Engineering Laboratory for Marine Algal Biotechnology, Guangdong Provincial Key Laboratory for Plant Epigenetics, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, ChinaMicroalgae are emerging as a key player in healthcare, functional foods, and sustainable biotech due to their capacity to produce bioactive compounds like β-glucans, omega-3 fatty acids, and antioxidants in an eco-friendly manner. This review comprehensively discusses the role of microalgae in healthcare and functional foods, focusing particularly on β-glucan therapeutics, drug delivery innovations, and synthetic biology applications. In healthcare, microalgae-derived compounds show immense promise for treating diseases, boosting immunity, and tackling oxidative stress. Euglena-derived paramylon, a type of β-glucan, has shown potential in various medical applications, including immunomodulation and anticancer therapy. Synthetic biology and bioprocess engineering are enhancing microalgae’s therapeutic and nutritional value, with applications in drug delivery and personalized medicine. To maximize the potential of microalgae, further research and development are needed to address scalability, regulatory alignment, and consumer acceptance, with a focus on interdisciplinary collaboration and sustainable practices to align healthcare innovation with environmental conservation.https://www.frontiersin.org/articles/10.3389/fphar.2025.1557298/fullmicroalgaehealth carefunctional foodsβ-glucandrug deliverysynthetic biology
spellingShingle Chao Li
Chao Li
Chao Li
Ming Du
Yujie Han
Wentao Sun
Zixi Chen
Qiong Liu
Hui Zhu
Liqing Zhao
Shuangfei Li
Jiangxin Wang
Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology
Frontiers in Pharmacology
microalgae
health care
functional foods
β-glucan
drug delivery
synthetic biology
title Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology
title_full Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology
title_fullStr Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology
title_full_unstemmed Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology
title_short Microalgae in health care and functional foods: β-glucan applications, innovations in drug delivery and synthetic biology
title_sort microalgae in health care and functional foods β glucan applications innovations in drug delivery and synthetic biology
topic microalgae
health care
functional foods
β-glucan
drug delivery
synthetic biology
url https://www.frontiersin.org/articles/10.3389/fphar.2025.1557298/full
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