Analysing dengue fever spread in Kenya using the Zero-Inflated Poisson model

Background: Dengue fever (DF), transmitted by Aedes mosquitoes, remains a major public health concern in tropical and subtropical regions. Understanding the influence of climatic variables on DF incidence is essential for improving outbreak prediction and control measures. Aim: This study analysed...

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Bibliographic Details
Main Authors: Lameck Ondieki Agasa, Faith Thuita, Thomas Achia, Antony Karanja
Format: Article
Language:English
Published: AOSIS 2025-02-01
Series:Journal of Public Health in Africa
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Online Access:https://publichealthinafrica.org/index.php/jphia/article/view/781
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Summary:Background: Dengue fever (DF), transmitted by Aedes mosquitoes, remains a major public health concern in tropical and subtropical regions. Understanding the influence of climatic variables on DF incidence is essential for improving outbreak prediction and control measures. Aim: This study analysed the impact of climatic factors on DF incidence in Kenya using a Zero-Inflated Poisson (ZIP) model. Setting: The study focused on DF cases in Kenya from 2019 to 2021. Methods: A ZIP model was applied to monthly dengue case data and associated climatic variables, such as temperature, rainfall, and humidity. The model addresses over-dispersion and excess zeros in the data, providing a more accurate depiction of DF dynamics. Results: The ZIP model revealed significant associations between climatic variables and DF incidence. Humidity (β = 0.0578, standard error [s.e.] = 0.0024, z = 24.157, p  2e-16) and temperature (β = 0.0558, s.e. = 0.0053, z = 10.497, p  0.01) showed a positive relationship with dengue cases, while rainfall (β = –0.0045, s.e. = 0.0003, z = –16.523, p  0.01) had a significant negative effect. The over-dispersion test confirmed excess variability in the data (O statistic = 456.3, p = 0.004), and the Vuong test supported the use of the ZIP model over a standard Poisson model. Model comparison indicated superior fit for the ZIP model (akaike information criterion [AIC] = 5230.959 vs. 27061.367 for Poisson), effectively accounting for zero-inflation. Conclusion: The results suggest that higher humidity and temperature favor dengue transmission, while heavy rainfall may disrupt mosquito breeding, reducing cases. These findings provide a basis for targeted public health interventions. Contribution: This study enhances understanding of DF-climate interactions in Kenya, supporting the application of ZIP modelling for improved disease surveillance and control strategies.
ISSN:2038-9922
2038-9930